Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-017-1551-3
Abstract: Expression of the hepatic peptide hormone hepcidin responds to iron levels via BMP/SMAD signaling, to inflammatory cues via JAK/STAT signaling, to the nutrient-sensing mTOR pathway, as well as to proliferative signals and gluconeogenesis. Here, we… read more here.
Keywords: citrate; metabolism; hormone hepcidin; expression ... See more keywords
The Discovery of the Iron-Regulatory Hormone Hepcidin.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical chemistry"
DOI: 10.1373/clinchem.2019.306407
Abstract: Featured Article: Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001;276:7806–10.2 Louis Pasteur's adage “Chance favors only the prepared mind” is a romantic… read more here.
Keywords: iron regulatory; discovery iron; regulatory hormone; hormone hepcidin ... See more keywords