LAUSR

Hormone-Inducible Transport Reporter Assay to Study Nuclear Import Defects in Neurodegenerative Diseases.

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0 Published in 2022 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-2337-4_5

Abstract: In the recent years, defective nuclear import has emerged as an important pathomechanism of neurodegenerative diseases, particularly in amyotrophic lateral sclerosis (ALS). Here, specific nuclear RNA binding proteins (RBPs) mislocalize and aggregate in the cytoplasm… read more here.

Keywords: import; hormone inducible; nuclear import; inducible transport ... See more keywords