A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300516
Abstract: The local application of drug-loaded bioactive scaffold materials is one of the important directions to solve the clinical problem of osteoporotic (OP) bone defects. This study retains the advantages of drug loading and mechanical properties… read more here.
Keywords: bone; related peptide; osteoporotic bone; parathyroid hormone ... See more keywords
Inhibition of epidermal growth factor receptor suppresses parathyroid hormone‐related protein expression in tumours and ameliorates cancer‐associated cachexia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12985
Abstract: Lung cancer is the primary cause of cancer deaths worldwide. Activation of epidermal growth factor receptor (EGFR) leads to lung cancer progression and poor prognosis while involuntary weight loss remains a major problem. Tumour‐derived parathyroid… read more here.
Keywords: epidermal growth; factor receptor; parathyroid hormone; growth factor ... See more keywords
Differential expression of hormone related genes between extreme segregants of a Saccharum interspecific F2 population
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DOI: 10.1007/s10681-018-2137-z
Abstract: Sugarcane is a highly productive, first generation biofuel feedstock, known for its remarkable efficiency in accumulating biomass. Hormones are important regulators for many biological processes in plants, especially in plant development and plant growth, which… read more here.
Keywords: plant; biomass; related genes; hormone related ... See more keywords
Molecular characterization of an adipokinetic hormone-related neuropeptide (AKH) from a mollusk.
Sign Up to like & getrecommendations! Published in 2017 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2016.11.002
Abstract: Adipokinetic hormones (AKH) are key regulators of energy mobilization in insects. With the growing number of genome sequence available, the existence of genes encoding AKH related peptides has now been established in protostomes. Here we… read more here.
Keywords: molecular characterization; characterization adipokinetic; adipokinetic hormone; hormone related ... See more keywords
Immunoarray Measurements of Parathyroid Hormone-Related Peptides Combined with Other Biomarkers to Diagnose Aggressive Prostate Cancer.
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DOI: 10.1021/acs.analchem.2c02648
Abstract: Parathyroid hormone-related peptide (PTHrP) is related to bone metastasis and hypercalcemia in prostate and breast cancers and should be an excellent biomarker for aggressive forms of these cancers. Current clinical detection protocols for PTHrP are… read more here.
Keywords: prostate cancer; prostate; parathyroid hormone; aggressive prostate ... See more keywords
Abstract 3062: Ablation of parathyroid hormone-related protein in the triple negative human breast cancer line MDA-MB-231 inhibits its cancer stem cell phenotype
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3062
Abstract: Parathyroid hormone-related protein (PTHrP) is a pleiotropic hormone involved in a wide range of developmental & physiological processes. It is also dysregulated in advanced cancers where it causes malignancy-associated hypercalcemia & plays a major role… read more here.
Keywords: hormone; parathyroid hormone; hormone related; related protein ... See more keywords
Sex hormone-related polymorphisms in endometriosis and migraine: A narrative review
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DOI: 10.1177/17455057221111315
Abstract: Some evidence indicates endometriosis and migraine have a common genetic predisposition in sex-hormone genes, which could have important implications for the treatment of these two heterogenous conditions. To date, the genes responsibility remains unknown. Based… read more here.
Keywords: endometriosis migraine; sex hormone; sex; hormone related ... See more keywords
Effect of parathyroid hormone-related protein on odontogenic differentiation in human dental pulp cells
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DOI: 10.1186/s12903-020-01085-8
Abstract: Background Parathyroid hormone-related protein (PTHrP) plays an important role in many physiological processes, including bone regeneration. The function of PTHrP is similar to PTH. It promotes osteogenic differentiation in MC3T3-E1 cells. The aim of this… read more here.
Keywords: pthrp; parathyroid hormone; odontogenic differentiation; differentiation ... See more keywords
An integrated study of hormone-related sarcopenia for modeling and comparative transcriptome in rats
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DOI: 10.3389/fendo.2023.1073587
Abstract: Sarcopenia is a senile disease with high morbidity, serious complications and limited clinical treatments. Menopause increases the risk of sarcopenia in females, while the exact pathogenesis remains unclear. To systematically investigate the development of hormone-related… read more here.
Keywords: sarcopenia; study hormone; hormone related; related sarcopenia ... See more keywords
Hormone-Related Cancer and Autoimmune Diseases: A Complex Interplay to be Discovered
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DOI: 10.3389/fgene.2021.673180
Abstract: Neoplasic transformation is a continuous process that occurs in the body. Even before clinical signs, the immune system is capable of recognizing these aberrant cells and reacting to suppress them. However, transformed cells acquire the… read more here.
Keywords: immune system; cancer; hormone related; autoimmune diseases ... See more keywords
The Impact of Homocysteine on the Risk of Hormone-Related Cancers: A Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2021.645371
Abstract: Background: Aberrant homocysteine level is associated with metabolic disorders and DNA damage, which may be involved in the carcinogenesis of hormone-related cancers, but clinical results of observational studies are controversial. In this study, we investigated… read more here.
Keywords: homocysteine; mendelian randomization; rcc; study ... See more keywords