Articles with "hormone secretagogue" as a keyword



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Detection of the growth hormone secretagogue MK-0677 in equine hair following oral administration.

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Published in 2022 at "Drug testing and analysis"

DOI: 10.1002/dta.3406

Abstract: MK-0677 (ibutamoren) is an orally active non-peptide growth hormone secretagogue that binds to the ghrelin receptor stimulating the secretion of endogenous growth hormone. It is one of the most prevalent performance-enhancing compounds currently available online… read more here.

Keywords: hair following; equine hair; hair; growth hormone ... See more keywords
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Energetic demands of lactation produce an increase in the expression of growth hormone secretagogue receptor in the hypothalamus and ventral tegmental area of the rat despite a reduction in circulating ghrelin

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Published in 2022 at "Journal of Neuroendocrinology"

DOI: 10.1111/jne.13126

Abstract: Lactating rats show changes in the secretion of hormones and brain signals that promote hyperphagia and facilitate the production of milk. Little is known, however, about the role of ghrelin in the mechanisms sustaining lactational… read more here.

Keywords: lactating rats; expression; growth hormone; ghrelin ... See more keywords
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Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12101370

Abstract: The gut peptide, ghrelin, mediates energy homeostasis and reproduction by acting through its receptor, growth hormone secretagogue receptor (GHSR), expressed in hypothalamic neurons in the arcuate (ARC). We have shown 17β-estradiol (E2) increases Ghsr expression… read more here.

Keywords: ghsr; ghrelin; growth hormone; secretagogue receptor ... See more keywords
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Establishment of a Cell Line Stably Expressing the Growth Hormone Secretagogue Receptor to Identify Crocin as a Ghrelin Agonist

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12121813

Abstract: The growth hormone secretagogue receptor-1a (GHSR1a) is the endogenous receptor for ghrelin. Activation of GHSR1a participates in many physiological processes including energy homeostasis and eating behavior. Due to its transitory half-life, the efficacy of ghrelin… read more here.

Keywords: ghsr1a; cell; growth hormone; secretagogue receptor ... See more keywords