Long-Term Survival After Transformation of an Adrenocorticotropic Hormone-Secreting Pituitary Macroadenoma to a Silent Corticotroph Pituitary Carcinoma.
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DOI: 10.1016/j.wneu.2018.11.011
Abstract: BACKGROUND Pituitary carcinomas are rare and aggressive neoplasms that despite current treatment regimens continue to have a poor prognosis. Adrenocorticotrophic hormone pituitary tumors have been shown to alter their clinical manifestations with conversion to Cushing… read more here.
Keywords: hormone; silent corticotroph; hormone secreting; secreting pituitary ... See more keywords
Management of hormone-secreting pituitary adenomas
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DOI: 10.1093/neuonc/now130
Abstract: Pituitary adenomas are one of the most common primary central nervous system tumors and have an estimated prevalence of 17%. Approximately half of pituitary adenomas secrete distinct pituitary hormones (most often prolactin, growth hormone, or… read more here.
Keywords: hormone; hormone secreting; secreting pituitary; pituitary adenomas ... See more keywords
Genetic and Epigenetic Characterization of Growth Hormone–Secreting Pituitary Tumors
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DOI: 10.1158/1541-7786.mcr-19-0434
Abstract: Somatic driver mechanisms of pituitary adenoma pathogenesis have remained incompletely characterized; apart from mutations in the stimulatory Gα protein (Gαs encoded by GNAS) causing activated cAMP synthesis, pathogenic variants are rarely found in growth hormone–secreting… read more here.
Keywords: secreting pituitary; gsp; growth hormone; hormone secreting ... See more keywords