Equination (inoculation of horsepox): An early alternative to vaccination (inoculation of cowpox) and the potential role of horsepox virus in the origin of the smallpox vaccine.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.11.003
Abstract: For almost 150 years after Edward Jenner had published the "Inquiry" in 1798, it was generally assumed that the cowpox virus was the vaccine against smallpox. It was not until 1939 when it was shown that… read more here.
Keywords: inoculation; vaccinia; horsepox; vaccine ... See more keywords
The De Novo Synthesis of Horsepox Virus: Implications for Biosecurity and Recommendations for Preventing the Reemergence of Smallpox.
Sign Up to like & getrecommendations! Published in 2017 at "Health security"
DOI: 10.1089/hs.2017.0061
Abstract: In March 2017, the American biotech company Tonix announced that a Canadian scientist had synthesized horsepox virus as part of a project to develop a safer vaccine against smallpox. The first de novo synthesis of… read more here.
Keywords: smallpox; horsepox; reemergence smallpox; virus ... See more keywords
Re-creation of Horsepox Virus
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DOI: 10.1128/msphere.00079-18
Abstract: Today, mSphere is publishing two commentaries on a controversial topic: should the horsepox virus have been reconstructed? A group led by David Evans at University of Alberta was funded by the company Tonix Pharmaceuticals, Inc.,… read more here.
Keywords: creation horsepox; horsepox virus; horsepox;
Re-assembly of nineteenth-century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the USA
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology"
DOI: 10.1186/s13059-020-02202-0
Abstract: According to a recent article published in Genome Biology, Duggan and coworkers sequenced and partially assembled five genomes of smallpox vaccines from the nineteenth century. No information regarding the ends of genomes was presented, and… read more here.
Keywords: smallpox vaccine; nineteenth century; biology; horsepox ... See more keywords