Equination (inoculation of horsepox): An early alternative to vaccination (inoculation of cowpox) and the potential role of horsepox virus in the origin of the smallpox vaccine.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.11.003
Abstract: For almost 150 years after Edward Jenner had published the "Inquiry" in 1798, it was generally assumed that the cowpox virus was the vaccine against smallpox. It was not until 1939 when it was shown that… read more here.
Keywords: inoculation; vaccinia; horsepox; vaccine ... See more keywords
Re-creation of Horsepox Virus
Sign Up to like & getrecommendations! Published in 2018 at "mSphere"
DOI: 10.1128/msphere.00079-18
Abstract: Today, mSphere is publishing two commentaries on a controversial topic: should the horsepox virus have been reconstructed? A group led by David Evans at University of Alberta was funded by the company Tonix Pharmaceuticals, Inc.,… read more here.
Keywords: creation horsepox; horsepox virus; horsepox;
Synthetic horsepox viruses and the continuing debate about dual use research
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007025
Abstract: On January 19, 2018, a paper describing the complete synthesis of a horsepox virus was published in PLOS ONE [1]. This is the largest virus assembled to date, and it shows that no viral pathogen… read more here.
Keywords: research; virus; biology; dual use ... See more keywords
Single Dose of Recombinant Chimeric Horsepox Virus (TNX-801) Vaccination Protects Macaques from Lethal Monkeypox Challenge
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15020356
Abstract: The ongoing global Monkeypox outbreak that started in the spring of 2022 has reinforced the importance of protecting the population using live virus vaccines based on the vaccinia virus (VACV). Smallpox also remains a biothreat… read more here.
Keywords: recombinant chimeric; single dose; tnx 801; chimeric horsepox ... See more keywords