Neisseria gonorrhoeae host adaptation and pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Microbiology"
DOI: 10.1038/nrmicro.2017.169
Abstract: The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of gonorrhoea. Consistent with its proposed evolution from an ancestral commensal bacterium, N. gonorrhoeae has retained features that are common in commensals, but it has… read more here.
Keywords: host adaptation; gonorrhoeae host; neisseria gonorrhoeae; host ... See more keywords
Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17407-x
Abstract: Avian influenza polymerase undergoes host adaptation in order to efficiently replicate in human cells. Adaptive mutants are localised on the C-terminal (627-NLS) domains of the PB2 subunit. In particular, mutation of PB2 residue 627 from… read more here.
Keywords: host adaptation; pb2; polymerase; anp32a ... See more keywords
Infection-elicited microbiota promotes host adaptation to nutrient restriction
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2214484120
Abstract: Significance The long-term impacts of infection on the microbiota and its regulation of host physiology are poorly understood. Here, we report that long-term alterations to the gut microbiota following a single, acute episode of bacterial… read more here.
Keywords: infection; host adaptation; infection elicited; elicited microbiota ... See more keywords
Mechanistic insights into host adaptation, virulence and epidemiology of the phytopathogen Xanthomonas
Sign Up to like & getrecommendations! Published in 2019 at "FEMS Microbiology Reviews"
DOI: 10.1093/femsre/fuz024
Abstract: ABSTRACT Xanthomonas is a well-studied genus of bacterial plant pathogens whose members cause a variety of diseases in economically important crops worldwide. Genomic and functional studies of these phytopathogens have provided significant understanding of microbial-host… read more here.
Keywords: host adaptation; virulence; epidemiology; host ... See more keywords
Shared Pathogenomic Patterns Characterize a New Phylotype, Revealing Transition toward Host-Adaptation Long before Speciation of Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2019 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evz162
Abstract: Abstract Tuberculosis remains one of the deadliest infectious diseases of humanity. To better understand the evolutionary history of host-adaptation of tubercle bacilli (MTB), we sought for mycobacterial species that were more closely related to MTB… read more here.
Keywords: host adaptation; mycobacterium tuberculosis; mycobacterium; host ... See more keywords
Genome reorganization during emergence of host-associated Mycobacterium abscessus
Sign Up to like & getrecommendations! Published in 2021 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000706
Abstract: Mycobacterium abscessus is a rapid growing, free-living species of bacterium that also causes lung infections in humans. Human infections are usually acquired from the environment; however, dominant circulating clones (DCCs) have emerged recently in both… read more here.
Keywords: mycobacterium abscessus; host adaptation; emergence host; host ... See more keywords
Intergenic evolution during host adaptation increases expression of the metallophore pseudopaline in Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2018 at "Microbiology"
DOI: 10.1099/mic.0.000687
Abstract: Regulating intracellular levels of biological metal ions is essential for all bacterial species, as they are needed for virulence and a range of metabolic processes. Zinc is the second most abundant metal ion in Pseudomonas… read more here.
Keywords: host adaptation; expression; pseudomonas aeruginosa; metal ion ... See more keywords
Experimentally evolved populations of the potato cyst nematode Globodera pallida allow the targeting of genomic footprints of selection due to host adaptation
Sign Up to like & getrecommendations! Published in 2017 at "Plant Pathology"
DOI: 10.1111/ppa.12646
Abstract: In the current agronomical context of pesticide use reduction, deciphering the genetic bases of pathogen adaptation to plant resistances is of major importance to improve their durability. Knowledge of the virulence gene frequencies in pathogens… read more here.
Keywords: host adaptation; pallida; globodera pallida; resistance ... See more keywords
Symbiotic microbes aid host adaptation by metabolizing a deterrent host pine carbohydrate d-pinitol in a beetle-fungus invasive complex
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.add5051
Abstract: The red turpentine beetle (RTB) is one of the most destructive invasive pests in China and solely consumes pine phloem containing high amounts of d-pinitol. Previous studies reported that d-pinitol exhibits deterrent effects on insects.… read more here.
Keywords: adaptation; host adaptation; pinitol; symbiotic microbes ... See more keywords
Convergent Within-Host Adaptation of Pseudomonas aeruginosa through the Transcriptional Regulatory Network
Sign Up to like & getrecommendations! Published in 2023 at "mSystems"
DOI: 10.1128/msystems.00024-23
Abstract: Pseudomonas aeruginosa causes significant morbidity and mortality. The pathogen's remarkable ability to establish chronic infections greatly depends on its adaptation to the host environment. ABSTRACT Bacteria adapt to their host by mutating specific genes and… read more here.
Keywords: network; adaptation; transcriptional regulatory; pseudomonas aeruginosa ... See more keywords
Phylodynamics and Molecular Mutations of the Hemagglutinin Affecting Global Transmission and Host Adaptation of H5Nx Viruses
Sign Up to like & getrecommendations! Published in 2023 at "Transboundary and Emerging Diseases"
DOI: 10.1155/2023/8855164
Abstract: Highly pathogenic avian influenza (HPAI) H5 viruses have circulated globally causing incidental human infection with a substantial pandemic threat. The present study investigated the molecular evolution and phylodynamics of hemagglutinin (HA) in avian and human-isolated… read more here.
Keywords: host adaptation; phylodynamics molecular; h5nx viruses; h5nx ... See more keywords