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   Articles with "host antiviral" as a keyword



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Host antiviral protein IFITM2 restricts pseudorabies virus replication

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recommendations! Published in 2020 at "Virus Research"

DOI: 10.1016/j.virusres.2020.198105

Abstract: Pseudorabies virus (PRV) is one of the most destructive swine pathogens and leads to huge economic losses to the global pig industry. Type I interferons (IFNs) plays a pivotal role in the innate immune response… read more here.

Keywords: antiviral protein; ifitm proteins; host antiviral; infection ... See more keywords

High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.

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recommendations! Published in 2021 at "EMBO reports"

DOI: 10.15252/embr.202153466

Abstract: High-salt diets have recently been implicated in hypertension, cardiovascular disease, and autoimmune disease. However, whether and how dietary salt affects host antiviral response remain elusive. Here, we report that high salt induces an instant reduction… read more here.

Keywords: antiviral immunity; host antiviral; high salt; salt ... See more keywords
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Skin Viral Infections: Host Antiviral Innate Immunity and Viral Immune Evasion

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recommendations! Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.593901

Abstract: The skin is an active immune organ that functions as the first and largest site of defense to the outside environment. Serving as the primary interface between host and pathogen, the skin’s early immune responses… read more here.

Keywords: host antiviral; viral infections; antiviral innate; infections host ... See more keywords

Myricetin inhibits pseudorabies virus infection through direct inactivation and activating host antiviral defense

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recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.985108

Abstract: Myricetin, a polyhydroxyflavone compound, is one of the main ingredients of various human foods and therefore also known as dietary flavonoids. Due to the continuous emergence of resistant strains of herpesviruses, novel control measures are… read more here.

Keywords: host antiviral; myricetin; infection; pseudorabies virus ... See more keywords

Herpes simplex virus type I glycoprotein L evades host antiviral innate immunity by abrogating the nuclear translocation of phosphorylated NF-κB sub-unit p65

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recommendations! Published in 2023 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2023.1178249

Abstract: Nuclear factor (NF)-κB plays an important role in the innate immune response by inducing antiviral genes’ expression. However, the herpes simplex virus 1 (HSV-1) virus has developed multiple ways to interfere with NF-κB activity to… read more here.

Keywords: host antiviral; translocation; p65; simplex virus ... See more keywords
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Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective

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recommendations! Published in 2020 at "Biomolecules"

DOI: 10.3390/biom10121591

Abstract: Nuclear DNA sensors are critical components of the mammalian innate immune system, recognizing the presence of pathogens and initiating immune signaling. These proteins act in the nuclei of infected cells by binding to foreign DNA,… read more here.

Keywords: dna sensors; dna; host antiviral; nuclear dna ... See more keywords
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Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication

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recommendations! Published in 2020 at "Viruses"

DOI: 10.3390/v12101093

Abstract: Influenza A virus is a major global pathogen of humans, and there is an unmet need for effective antivirals. Current antivirals against influenza A virus directly target the virus and are vulnerable to mutational resistance.… read more here.

Keywords: response; host antiviral; antiviral response; blocks influenza ... See more keywords

Modulation of HIV Replication in Monocyte-Derived Macrophages (MDM) by Host Antiviral Factors Secretory Leukocyte Protease Inhibitor and Serpin Family C Member 1 Induced by Steroid Hormones

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recommendations! Published in 2022 at "Viruses"

DOI: 10.3390/v14010095

Abstract: The impact of steroid hormones estrogen and progesterone on human immunodeficiency virus type 1 (HIV-1) replication is well documented. However, the exact mechanism involved in the regulation of HIV-1 replication by estrogen and progesterone is… read more here.

Keywords: host antiviral; hiv replication; hiv; protease inhibitor ... See more keywords

Myxoma Virus-Encoded Host Range Protein M029: A Multifunctional Antagonist Targeting Multiple Host Antiviral and Innate Immune Pathways

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recommendations! Published in 2020 at "Vaccines"

DOI: 10.3390/vaccines8020244

Abstract: Myxoma virus (MYXV) is the prototypic member of the Leporipoxvirus genus of the Poxviridae family of viruses. In nature, MYXV is highly restricted to leporids and causes a lethal disease called myxomatosis only in European… read more here.

Keywords: host antiviral; antiviral innate; host; myxoma virus ... See more keywords