Clearance or Hijack: Universal Interplay Mechanisms Between Viruses and Host Autophagy From Plants to Animals
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.786348
Abstract: Viruses typically hijack the cellular machinery of their hosts for successful infection and replication, while the hosts protect themselves against viral invasion through a variety of defense responses, including autophagy, an evolutionarily ancient catabolic pathway… read more here.
Keywords: plants animals; interplay mechanisms; host autophagy; hijack universal ... See more keywords
Host autophagy machinery is diverted to the pathogen interface to mediate focal defense responses against the Irish potato famine pathogen
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.37476
Abstract: During plant cell invasion, the oomycete Phytophthora infestans remains enveloped by host-derived membranes whose functional properties are poorly understood. P. infestans secretes a myriad of effector proteins through these interfaces for plant colonization. Recently we… read more here.
Keywords: pathogen; host autophagy; autophagy machinery; host ... See more keywords
Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.69047
Abstract: Autophagy acts as a pivotal innate immune response against infection. Some virulence effectors subvert the host autophagic machinery to escape the surveillance of autophagy. The mechanism by which pathogens interact with host autophagy remains mostly… read more here.
Keywords: attenuates host; incorporated crosslinkers; genetically incorporated; psmd10 ... See more keywords