Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation.
Sign Up to like & getrecommendations! Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2020.04.017
Abstract: The bacterium Pseudomonas aeruginosa is especially pathogenic, often being associated with intractable pneumonia and high mortality. How P.Ā aeruginosa avoids immune clearance and persists in the inflamed human airway remains poorly understood. In this study, we… read more here.
Keywords: pseudomonas aeruginosa; host; biofilm formation; host derived ... See more keywords
Putative host-derived growth factor inducing colonization of Burkholderia gut symbiont in Riptortus insecticola insect.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2019.103570
Abstract: It is questionable that how gut symbiont can be proliferated in the host symbiotic organs, such as host midgut region, which are known to be highly stressful and nutritional depleted conditions. Since Riptortus-Burkholderia symbiosis system… read more here.
Keywords: growth factor; host; gut symbiont; host derived ... See more keywords
Lipase-mediated detoxification of host-derived antimicrobial fatty acids by Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06278-3
Abstract: Long-chain fatty acids with antimicrobial properties are abundant on the skin and mucosal surfaces, where they are essential to restrict the proliferation of opportunistic pathogens such as Staphylococcus aureus. These antimicrobial fatty acids (AFAs) elicit… read more here.
Keywords: host derived; detoxification; lipase; antimicrobial fatty ... See more keywords
Inhibition of histone acetyltransferase GCN5 by a transcription factor FgPacC controls fungal adaption to host-derived iron stress
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac498
Abstract: Abstract Poaceae plants can locally accumulate iron to suppress pathogen infection. It remains unknown how pathogens overcome host-derived iron stress during their successful infections. Here, we report that Fusarium graminearum (Fg), a destructive fungal pathogen… read more here.
Keywords: iron stress; iron; transcription factor; host derived ... See more keywords
Microbial and host-derived biomarker changes during ligature-induced and spontaneous peri-implantitis in the Beagle dog.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of periodontal research"
DOI: 10.1111/jre.12797
Abstract: OBJECTIVE To evaluate microbial and host-derived biomarker changes during experimental peri-implantitis in the Beagle dog. BACKGROUND Limited data exist on the microbial and biomarker changes during progressive bone loss as result of experimental peri-implantitis. METHODS… read more here.
Keywords: biomarker changes; host derived; implantitis; peri implantitis ... See more keywords
Rickettsial pathogen augments tick vesicular-associated membrane proteins for infection and survival in the vector host
Sign Up to like & getrecommendations! Published in 2025 at "mBio"
DOI: 10.1128/mbio.03549-24
Abstract: ABSTRACT Anaplasma phagocytophilum is an obligate intracellular rickettsial pathogen that infects humans and animals. The black-legged tick Ixodes scapularis acts as a vector and transmits this bacterium to the vertebrate host. Upon entry into a… read more here.
Keywords: tick cells; host; phagocytophilum; host derived ... See more keywords
Putative Host-Derived Insertions in the Genomes of Circulating SARS-CoV-2 Variants
Sign Up to like & getrecommendations! Published in 2022 at "mSystems"
DOI: 10.1128/msystems.00179-22
Abstract: Throughout the COVID-19 pandemic, the sequencing of SARS-CoV-2 genomes has revealed the presence of insertions in multiple globally circulating lineages of SARS-CoV-2, including the Omicron variant. The human genome has been suggested to be the… read more here.
Keywords: derived insertions; cov genome; circulating sars; host derived ... See more keywords
A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer"
DOI: 10.1186/s12943-017-0616-9
Abstract: Matrix metalloproteinases (MMPs) play a critical role in cancer pathogenesis, including tumor growth and osteolysis within the bone marrow microenvironment. However, the anti-tumor effects of MMPs are poorly understood, yet have significant implications for the… read more here.
Keywords: derived mmp; host derived; bone; host ... See more keywords
Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006475
Abstract: Amphipathic Ī±-helices of exchangeable apolipoproteins have shown to play crucial roles in the formation of infectious hepatitis C virus (HCV) particles through the interaction with viral particles. Among the Flaviviridae members, pestivirus and flavivirus possess… read more here.
Keywords: particle formation; erns ns1; host derived; formation infectious ... See more keywords
Regulation of MAIT cells through host-derived antigens
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1424987
Abstract: Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells that function at the interface between innate and acquired immunity. MAIT cells recognize vitamin B2-related metabolites produced by microbes, through semi-invariant T… read more here.
Keywords: derived antigens; mait cells; host derived; regulation mait ... See more keywords
Multi-Omics Characterization of Host-Derived Bacillus spp. Probiotics for Improved Growth Performance in Poultry
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.747845
Abstract: Microbial feed ingredients or probiotics have been used widely in the poultry industry to improve production efficiency. Spore-forming Bacillus spp. offer advantages over traditional probiotic strains as Bacillus spores are resilient to high temperature, acidic… read more here.
Keywords: multi omics; host derived; omics characterization; growth ... See more keywords