Pre-Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft-Versus-Host Disease in Systemic Organs.
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DOI: 10.1002/advs.202415982
Abstract: Acute graft-versus-host disease (aGvHD) remains a significant clinical challenge, with no optimal treatment despite advancements in medical science. This life-threatening condition, characterized by multi-organ involvement and high mortality, is increasingly linked to the gut microbiota.… read more here.
Keywords: disease; host disease; administration; versus host ... See more keywords
A population‐based study of outcomes in polycythemia vera, essential thrombocythemia, and primary myelofibrosis in the United States from 2001 to 2015: Comparison with data from a Mayo Clinic single institutional series
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DOI: 10.1002/ajh.26377
Abstract: REFERENCES 1. Westin JR, Saliba RM, De Lima M, et al. Steroid-refractory acute GVHD: predictors and outcomes. Adv Hematol. 2011;2011:601953-601958. 2. MacMillan ML, DeFor TE, Weisdorf DJ. What predicts high risk acute graft-versus-host disease (GVHD)… read more here.
Keywords: gvhd; acute; study; host disease ... See more keywords
Toward Improving Initial Therapy of Acute Graft Versus Host Disease
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DOI: 10.1002/ajh.27593
Abstract: Acute graft versus host disease (aGVHD) is a major complication of hematopoietic stem cell transplantation; it results from donor‐derived immune response against host tissues and typically involves the liver, skin and the GI tract. The… read more here.
Keywords: host; host disease; versus host; graft versus ... See more keywords
Patient‐reported symptom burden and impact on daily activities in chronic graft‐versus‐host disease
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DOI: 10.1002/cam4.5209
Abstract: Chronic graft‐versus‐host disease (GVHD) is a potentially life‐threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT) treatment for hematologic malignancies. There are limited patient‐reported data concerning symptom burden and effects on activities of daily living… read more here.
Keywords: symptom burden; chronic graft; patient reported; host disease ... See more keywords
Monitoring plasma regenerating islet-derived 3α and citrulline levels during pediatric allogeneic hematopoietic stem cell transplantation to predict acute gastrointestinal graft-versus-host disease.
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DOI: 10.1002/ijc.70205
Abstract: Acute graft‐versus‐host disease (aGvHD) with gastrointestinal (GI) involvement is a significant cause of transplant‐related morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HSCT). Although elevated plasma Regenerating islet‐derived 3α (REG3α) and reduced citrulline levels… read more here.
Keywords: citrulline; host disease; citrulline levels; versus host ... See more keywords
Role of extracorporeal photopheresis in the management of children with graft‐vs‐host disease
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DOI: 10.1002/jca.22012
Abstract: Graft‐vs‐host disease (GVHD) is a frequent cause of morbidity and mortality in allogeneic stem cell transplants. Extracorporeal photopheresis (ECP) is one of the most accepted second‐line treatments, but technical issues of ECP in children might… read more here.
Keywords: extracorporeal photopheresis; host disease; graft host;
Noncoding RNAs in diagnosis and prognosis of graft‐versus‐host disease (GVHD)
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DOI: 10.1002/jcp.30830
Abstract: Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a functional therapy for a plethora of hematologic malignancies and immune disorders. Graft‐versus‐host disease (GVHD), on the other hand, is one of the major complications ahead of a… read more here.
Keywords: host disease; versus host; noncoding rnas; graft versus ... See more keywords
Functional dosing of mesenchymal stromal cell‐derived extracellular vesicles for the prevention of acute graft‐versus‐host‐disease
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DOI: 10.1002/stem.3160
Abstract: Graft‐vs‐host‐disease (GvHD) is currently the main complication of allogeneic hematopoietic stem cell transplantation. Mortality and morbidity rates are particularly high, especially in steroid‐refractory acute GvHD (aGvHD). Immune regulatory human bone marrow mesenchymal stromal cells (hMB‐MSCs)… read more here.
Keywords: extracellular vesicles; mesenchymal stromal; hbm msc; graft ... See more keywords
Microbiome: an emerging new frontier in graft‑versus‑host disease
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DOI: 10.1007/s00011-020-01419-w
Abstract: The field around the microbiome and graft-versus-host disease (GVHD) is rapidly evolving and so is its literature. Therefore, we consider it important to provide an update on our recent review “Microbiome: An Emerging New Frontier… read more here.
Keywords: versus host; graft versus; host; host disease ... See more keywords
Compound heterozygous DCLRE1C mutations lead to clinically typical Severe Combined Immunodeficiency presenting with Graft Versus Host Disease.
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DOI: 10.1007/s00251-021-01219-4
Abstract: Artemis (DCLRE1C) is involved in opening recombination-activating gene (RAG1/RAG2)-generated hairpins during V(D)J recombination, an essential process for the differentiation and maturation of T and B cells. Here, we reported a case of 5-month-old boy with… read more here.
Keywords: versus host; combined immunodeficiency; host disease; compound heterozygous ... See more keywords
High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease
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DOI: 10.1007/s00277-020-04347-1
Abstract: Antithymocyte globulin (ATG) reduces severe acute and chronic graft-versus-host disease (GVHD) in allogeneic peripheral blood stem cell transplantation (PBSCT). However, risk factors for severe acute GVHD in PBSCT using ATG remain to be determined. We… read more here.
Keywords: lymphocyte counts; alc atg; versus host; host disease ... See more keywords