Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes
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DOI: 10.1126/sciadv.aau8408
Abstract: Natural triterpenoids, as virus-host fusion inhibitors, exhibit potential in expanding the current repertoire of antiviral agents. A trimer-of-hairpins motif has been identified in triggering virus-cell fusion within a variety of viral envelopes. Chemically manipulating such… read more here.
Keywords: virus host; host fusion; viral envelopes; fusion ... See more keywords