Long non‐coding small nucleolar RNA host genes in digestive cancers
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2622
Abstract: Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs… read more here.
Keywords: coding small; small nucleolar; long non; host genes ... See more keywords
The effects of nested miRNAs and their host genes on immune defense against Bacillus thuringiensis infection in Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104144
Abstract: microRNAs (miRNAs) are small non-coding RNA-molecules that influence translation by binding to the target gene mRNA. Many miRNAs are found in nested arrangements within larger protein-coding host genes. miRNAs and host genes in a nested… read more here.
Keywords: defense; infection; host genes; host ... See more keywords
Evolutionary Epigenomics of Retrotransposon-Mediated Methylation Spreading in Rice
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msx284
Abstract: &NA; Plant genomes contain numerous transposable elements (TEs), and many hypotheses on the evolutionary drivers that restrict TE activity have been postulated. Few models, however, have focused on the evolutionary epigenomic interaction between the plant… read more here.
Keywords: methylation; evolutionary epigenomics; host genes; epigenomics retrotransposon ... See more keywords
HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00381-23
Abstract: This study provides a genome-wide analysis of changes in promoter-proximal polymerase II (Pol II) pausing on host genes induced by HSV-1 infection. It shows that standard measures of pausing, i.e., pausing indices, do not properly… read more here.
Keywords: infection; hsv infection; promoter proximal; pol pausing ... See more keywords
23 Study on mirnas prediction and co-expression patterns of the human intronic mirnas with their host genes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Investigative Medicine"
DOI: 10.1136/jim-2017-mebabstracts.23
Abstract: Objectives MiRNAs are a set of endogenous non-coding RNAs with a length of about 22nt. They regulate the expression of the target mRNAs and are involved in many important biological processes including metabolism, defense against… read more here.
Keywords: intronic mirnas; host genes; expression; prediction ... See more keywords
Identification of infectious disease-associated host genes using machine learning techniques
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3317-0
Abstract: BackgroundWith the global spread of multidrug resistance in pathogenic microbes, infectious diseases emerge as a key public health concern of the recent time. Identification of host genes associated with infectious diseases will improve our understanding… read more here.
Keywords: infectious disease; associated host; disease; host genes ... See more keywords
Transcriptional and reverse transcriptional regulation of host genes by human endogenous retroviruses in cancers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.946296
Abstract: Human endogenous retroviruses (HERVs) originated from ancient retroviral infections of germline cells millions of years ago and have evolved as part of the host genome. HERVs not only retain the capacity as retroelements but also… read more here.
Keywords: human endogenous; regulation host; transcriptional regulation; host ... See more keywords
An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.00389
Abstract: The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which are reported in many studies as being overexpressed in various cancers. With very few exceptions, the SNHGs (SNHG1, SNHG3, SNHG5,… read more here.
Keywords: class; rna; long non; host genes ... See more keywords
“What You Need, Baby, I Got It”: Transposable Elements as Suppliers of Cis-Operating Sequences in Drosophila
Sign Up to like & getrecommendations! Published in 2020 at "Biology"
DOI: 10.3390/biology9020025
Abstract: Transposable elements (TEs) are constitutive components of both eukaryotic and prokaryotic genomes. The role of TEs in the evolution of genes and genomes has been widely assessed over the past years in a variety of… read more here.
Keywords: baby got; host genes; model; biology ... See more keywords
COVID-GWAB: A Web-Based Prediction of COVID-19 Host Genes via Network Boosting of Genome-Wide Association Data
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101446
Abstract: Host genetics affect both the susceptibility and response to viral infection. Searching for host genes that contribute to COVID-19, the Host Genetics Initiative (HGI) was formed to investigate the genetic factors involved in COVID-19 via… read more here.
Keywords: covid; covid gwab; association; host genes ... See more keywords
CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2018 at "Viruses"
DOI: 10.3390/v10010040
Abstract: Currently, a new gene editing tool—the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated (Cas) system—is becoming a promising approach for genetic manipulation at the genomic level. This simple method, originating from the adaptive immune… read more here.
Keywords: genes antiviral; antiviral strategy; crispr cas; cas ... See more keywords