The Role of Host Genetic Polymorphisms in Helicobacter pylori Mediated Disease Outcome.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2019_364
Abstract: The clinical outcome of infection with the chronic gastric pathogen Helicobacter pylori is not the same for all individuals and also differs in different ethnic groups. Infection occurs in early life ( read more here.
Keywords: host genetic; genetic polymorphisms; infection; role ... See more keywords
Host Genetic Signatures of Susceptibility to Fungal Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2018_113
Abstract: Our relative inability to predict the development of fungal disease and its clinical outcome raises fundamental questions about its actual pathogenesis. Several clinical risk factors are described to predispose to fungal disease, particularly in immunocompromised… read more here.
Keywords: fungal disease; host genetic; disease; genetic signatures ... See more keywords
Host-Genetic-Based Outcome of Coinfection by PCV2b and PRRSV in Pigs.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of animal science"
DOI: 10.1093/jas/skad164
Abstract: Replication of porcine circovirus type 2 (PCV2), an important worldwide swine pathogen, has been demonstrated to be influenced by host genotype. Specifically, a missense DNA polymorphism (SYNGR2 p.Arg63Cys) within the SYNGR2 gene was demonstrated to… read more here.
Keywords: syngr2 63cys; prrsv; histology; syngr2 ... See more keywords
Genome‐wide association study for host genetic factors associated with equine herpesvirus type‐1 induced myeloencephalopathy
Sign Up to like & getrecommendations! Published in 2020 at "Equine Veterinary Journal"
DOI: 10.1111/evj.13261
Abstract: Abstract Background Equid herpesvirus (EHV‐1) infections in horses can lead to equine herpesvirus myeloencephalopathy (EHM), characterised by neurological clinical signs. The sporadic occurrence of the disease in horse herds suggests a host genetic component. A… read more here.
Keywords: host genetic; study; association; equine herpesvirus ... See more keywords
Host genetic determinants of the gut microbiota of wild mice
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Ecology"
DOI: 10.1111/mec.15139
Abstract: Identifying a common set of genes that mediate host–microbial interactions across populations and species of mammals has broad relevance for human health and animal biology. However, the genetic basis of the gut microbial composition in… read more here.
Keywords: host genetic; wild mice; gut microbial; host ... See more keywords
Host genetic factors associated with the range limit of a European hantavirus.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular ecology"
DOI: 10.1111/mec.16211
Abstract: The natural host ranges of many viruses are restricted to very specific taxa. Little is known about the molecular barriers between species that lead to the establishment of this restriction or generally prevent virus emergence… read more here.
Keywords: range limit; host genetic; genetic factors; factors associated ... See more keywords
PO 8355 HOST GENETIC POLYMORPHISMS AND ASYMPTOMATIC MALARIA IN SOUTHERN GHANA
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Global Health"
DOI: 10.1136/bmjgh-2019-edc.74
Abstract: Background Despite several interventions through malaria control programmes, asymptomatic malaria is a major barrier to control as asymptomatic individuals serve as reservoirs from which others are re-infected. The mechanism by which these individuals remain asymptomatic… read more here.
Keywords: genetic polymorphisms; southern ghana; host genetic; association ... See more keywords
Erratum: Methods for detecting host genetic modifiers of tumor vascular function using dynamic near-infrared fluorescence imaging: errata.
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical optics express"
DOI: 10.1364/boe.9.002543
Abstract: [This corrects the article on p. 543 in vol. 9, PMID: 29552392.]. read more here.
Keywords: erratum methods; methods detecting; host genetic; genetic modifiers ... See more keywords
Comparative Genome Sequencing Reveals Within-Host Genetic Changes in Neisseria meningitidis during Invasive Disease
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169892
Abstract: Some members of the physiological human microbiome occasionally cause life-threatening disease even in immunocompetent individuals. A prime example of such a commensal pathogen is Neisseria meningitidis, which normally resides in the human nasopharynx but is… read more here.
Keywords: host genetic; within host; disease; host ... See more keywords
Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler’s Murine Encephalomyelitis Virus (TMEV) infection
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DOI: 10.1371/journal.pone.0256370
Abstract: Host genetic background is a significant driver of the variability in neurological responses to viral infection. Here, we leverage the genetically diverse Collaborative Cross (CC) mouse resource to better understand how chronic infection by Theiler’s… read more here.
Keywords: host genetic; infection; lesion distribution; theiler murine ... See more keywords
Absence of association between host genetic mutations in the ORAI1 gene and COVID-19 fatality
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0263303
Abstract: The calcium ion channel ORAI1 has emerged as a promising therapeutic target for the Coronavirus Disease 19 (COVID-19)-associated pneumonia, and a pharmacological inhibitor of ORAI1 has now reached clinical trials for severe COVID-19 pneumonia. Whether… read more here.
Keywords: association host; orai1; host genetic; covid fatality ... See more keywords