Host genetics in malaria: lessons from mouse studies
Sign Up to like & getrecommendations! Published in 2018 at "Mammalian Genome"
DOI: 10.1007/s00335-018-9744-9
Abstract: Malaria remains a deadly parasitic disease caused by Plasmodium, claiming almost half a million lives every year. While parasite genetics and biology are often the major targets in many studies, it is becoming more evident… read more here.
Keywords: mouse models; genetics malaria; malaria lessons; genetics ... See more keywords
Host genetics of innate immune system in infection.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.11.003
Abstract: The innate immune system is critical for initial recognition of infectious pathogens. Herein we highlight pathways critical to innate immunity as defined by the latest genetic findings. Several genes previously known to have recessive diseases… read more here.
Keywords: host genetics; genetics; infection; innate immune ... See more keywords
The influence of host genetics on liver microbiome composition in patients with NAFLD
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103858
Abstract: Summary Background Human body microbiotas are influenced by several factors, including the interaction of the host with the environment and dietary preferences. The role of host genetics in modulating the liver microbiota in the context… read more here.
Keywords: genetics liver; influence host; host genetics; genetics ... See more keywords
Host Genetics and Gut Microbiome: Challenges and Perspectives.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in immunology"
DOI: 10.1016/j.it.2017.06.003
Abstract: The mammalian gut is colonized by trillions of microorganisms collectively called the microbiome. It is increasingly clear that this microbiome has a critical role of in many aspects of health including metabolism and immunity. While… read more here.
Keywords: genetics; microbiome challenges; host genetics; genetics gut ... See more keywords
Host genetics in susceptibility to and severity of mycobacterial diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Tuberculosis"
DOI: 10.1016/j.tube.2017.05.004
Abstract: The genetic analysis of susceptibility to infections has proven to be extremely useful for identification of key cells, molecules, pathways, and genes involved in the battle between two genomes - the essence of the infectious… read more here.
Keywords: susceptibility; genetics; severity mycobacterial; host genetics ... See more keywords
Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project.
Sign Up to like & getrecommendations! Published in 2022 at "Nature genetics"
DOI: 10.1038/s41588-021-00992-y
Abstract: Host genetics are known to influence the gut microbiome, yet their role remains poorly understood. To robustly characterize these effects, we performed a genome-wide association study of 207 taxa and 205 pathways representing microbial composition… read more here.
Keywords: 738 participants; gut microbiome; host genetics; genetics ... See more keywords
The Relative Contributions of the Gut Microbiome, Host Genetics, and Environment to Cytokine Responses to Microbial Stimulation.
Sign Up to like & getrecommendations! Published in 2017 at "Gastroenterology"
DOI: 10.1053/j.gastro.2017.04.037
Abstract: Marcia Cruz-Correa, Section Editor David Schwartz, Section Editor 65 66 STAFF OF CONTRIBUTORS 67 68 69 70 71 72 73 74 75 Joseph Anderson, White River Junction, VT Johanna L. Chan, Houston, TX Matthew A.… read more here.
Keywords: relative contributions; genetics; host genetics; contributions gut ... See more keywords
Host genetics, phenotype and geography structure the microbiome of a foundational seaweed
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Ecology"
DOI: 10.1111/mec.16378
Abstract: Interactions between hosts and their microbiota are vital to the functioning and resilience of macro‐organisms. Critically, for hosts that play foundational roles in communities, understanding what drives host–microbiota interactions is essential for informing ecosystem restoration… read more here.
Keywords: host genetics; geography; foundational seaweed; genetics ... See more keywords
How host genetics dictates successful viral zoonosis
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000217
Abstract: Viruses of wild and domestic animals can infect humans in a process called zoonosis, and these events can give rise to explosive epidemics such as those caused by the HIV and Ebola viruses. While humans… read more here.
Keywords: genetics; zoonosis; animal viruses; host genetics ... See more keywords
The changing influence of host genetics on the leaf fungal microbiome throughout plant development
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001748
Abstract: Host genetics and the environment influence which fungal microbes colonize a plant. A new study in PLOS Biology finds that the relative influence of these factors changes throughout the development of the biofuel crop switchgrass… read more here.
Keywords: influence; host genetics; plant; biology ... See more keywords
Association of host genetics with intestinal microbial relevant to body weight in a chicken F2 resource population.
Sign Up to like & getrecommendations! Published in 2019 at "Poultry science"
DOI: 10.3382/ps/pez199
Abstract: Host-microbiota interactions describe a co-evolution and mutualistic symbiosis. Gut microbial communities are important for diverse host functions. However, in birds, the relationship between the composition of the intestinal microbiota and the genetic variation of the… read more here.
Keywords: population; microbiota; body weight; genetics ... See more keywords