HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Virus research"
DOI: 10.1016/j.virusres.2017.01.016
Abstract: The cellular antiviral innate immune system is essential for host defense and viruses have evolved a variety of strategies to evade the innate immunity. Human T lymphotropic virus type 1 (HTLV-1) belongs to the deltaretrovirus… read more here.
Keywords: innate; htlv; tax; host innate ... See more keywords
MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123208119
Abstract: Significance Middle East respiratory syndrome coronavirus (MERS-CoV) causes highly lethal respiratory disease. MERS-CoV encodes innate immune antagonists, including accessory proteins NS4a and NS4b, unique to the merbeco lineage of betacoronaviruses, and the nsp15 protein endoribonuclease… read more here.
Keywords: host innate; innate immunity; mers cov; accessory proteins ... See more keywords
The pathogenic biomarker alcohol dehydrogenase protein is involved in Bacillus cereus virulence and survival against host innate defence
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DOI: 10.1371/journal.pone.0259386
Abstract: Bacillus cereus is a spore forming bacteria recognized among the leading agents responsible for foodborne outbreaks in Europe. B. cereus is also gaining notoriety as an opportunistic human pathogen inducing local and systemic infections. The… read more here.
Keywords: host innate; bacillus cereus; alcohol dehydrogenase; virulence ... See more keywords
The Role of Deubiquitinases in Virus Replication and Host Innate Immune Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.839624
Abstract: As a critical post-translational modification, ubiquitination is known to affect almost all the cellular processes including immunity, signaling pathways, cell death, cancer development, and viral infection by controlling protein stability. Deubiquitinases (DUBs) cleave ubiquitin from… read more here.
Keywords: host innate; immune response; innate immune; role ... See more keywords
Roles of RNA Sensors in Host Innate Response to Influenza Virus and Coronavirus Infections
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158285
Abstract: Influenza virus and coronavirus are two important respiratory viruses, which often cause serious respiratory diseases in humans and animals after infection. In recent years, highly pathogenic avian influenza virus (HPAIV) and SARS-CoV-2 have become major… read more here.
Keywords: host innate; influenza; influenza virus; virus coronavirus ... See more keywords
Subversion of Host Innate Immunity by Human Papillomavirus Oncoproteins
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DOI: 10.3390/pathogens9040292
Abstract: The growth of human papillomavirus (HPV)-transformed cells depends on the ability of the viral oncoproteins E6 and E7, especially those from high-risk HPV16/18, to manipulate the signaling pathways involved in cell proliferation, cell death, and… read more here.
Keywords: innate; innate immunity; host innate; human papillomavirus ... See more keywords
The Interplay between Host Innate Immunity and Hepatitis E Virus
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11060541
Abstract: Hepatitis E virus (HEV) infection represents an emerging global health issue, whereas the clinical outcomes vary dramatically among different populations. The host innate immune system provides a first-line defense against the infection, but dysregulation may… read more here.
Keywords: host innate; innate immunity; host; hepatitis virus ... See more keywords
Modulation of Innate Immune Signaling Pathways by Herpesviruses
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DOI: 10.3390/v11060572
Abstract: Herpesviruses can be detected by pattern recognition receptors (PRRs), which then activate downstream adaptors, kinases and transcription factors (TFs) to induce the expression of interferons (IFNs) and inflammatory cytokines. IFNs further activate the Janus kinase-signal… read more here.
Keywords: signaling pathways; infection; host innate; immune signaling ... See more keywords
Hepatitis E Virus: How It Escapes Host Innate Immunity
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DOI: 10.3390/vaccines8030422
Abstract: Hepatitis E virus (HEV) is a leading cause of viral hepatitis in the world. It is usually responsible for acute hepatitis, but can lead to a chronic infection in immunocompromised patients. The host’s innate immune… read more here.
Keywords: hepatitis; hev; hepatitis virus; host innate ... See more keywords