Cross-testing of direct-action antivirals, universal vaccines, or search for host-level antivirals: what will sooner lead to a generic capability to combat the emerging viral pandemics?
Sign Up to like & getrecommendations! Published in 2021 at "Expert review of anti-infective therapy"
DOI: 10.1080/14787210.2022.2000859
Abstract: INTRODUCTION Mitigation of future viral pandemics is an enormous technical problem, but its solution is essential for preservation of life, economic well-being, and social stability. The author examined host-level, direct action antiviral, and universal vaccine… read more here.
Keywords: viral pandemics; action antivirals; direct action; host level ... See more keywords
Host-Level Susceptibility and IRF1 Expression Influence the Ability of IFN-γ to Inhibit KSHV Infection in B Lymphocytes
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DOI: 10.3390/v14102295
Abstract: Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with vascular endothelial cell tumor, Kaposi’s sarcoma (KS) and lymphoproliferative disorder, multicentric Castleman’s disease (MCD), primary effusion lymphoma (PEL) and KSHV inflammatory cytokine syndrome (KICS). Dysregulation of proinflammatory cytokines… read more here.
Keywords: kshv infection; susceptibility irf1; infection; level susceptibility ... See more keywords