Chemical Proteomics of Host–Microbe Interactions
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700333
Abstract: The dynamic proteome plays numerous roles in the interactions of microbes—whether they are invading pathogens or symbiotic organisms—and their hosts. Host and microbe sense, respond, and manipulate each other's biology via a multitude of mechanisms,… read more here.
Keywords: proteomics host; microbe; chemical proteomics; microbe interactions ... See more keywords
The role of gut microbiota in health and disease: In vitro modeling of host-microbe interactions at the aerobe-anaerobe interphase of the human gut.
Sign Up to like & getrecommendations! Published in 2017 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2017.01.001
Abstract: The microbiota of the gut has many crucial functions in human health. Dysbiosis of the microbiota has been correlated to a large and still increasing number of diseases. Recent studies have mostly focused on analyzing… read more here.
Keywords: gut; human gut; disease; host microbe ... See more keywords
Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.08.003
Abstract: Summary Metformin is the first-line therapy for treating type 2 diabetes and a promising anti-aging drug. We set out to address the fundamental question of how gut microbes and nutrition, key regulators of host physiology,… read more here.
Keywords: metformin; drug; drug nutrient; host microbe ... See more keywords
Host–Microbe Interactions: Winning the Colonization Lottery
Sign Up to like & getrecommendations! Published in 2017 at "Current Biology"
DOI: 10.1016/j.cub.2017.05.068
Abstract: Stochastic bottlenecks during bacterial colonization of animal hosts lead to reduced genetic diversity in the resulting microbiota and, at low-inoculation doses, can result in hosts that remain uncolonized. Bacterial strains vary in their colonization efficiency… read more here.
Keywords: colonization lottery; microbe interactions; colonization; host microbe ... See more keywords
Resolving host-microbe interactions in the gut: the promise of in vitro models to complement in vivo research.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2018.07.001
Abstract: While animal models remain essential for inferring causality, they exhibit important limitations, which restrict the direct translation of findings into new approaches aimed at steering host-microbe interactions for the improvement of human health. Different in… read more here.
Keywords: microbe; microbe interactions; interactions gut; host microbe ... See more keywords
Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe.
Sign Up to like & getrecommendations! Published in 2018 at "Methods"
DOI: 10.1016/j.ymeth.2018.04.029
Abstract: It is well established that gut microbes and their metabolic products regulate host metabolism. The interactions between the host and its gut microbiota are highly dynamic and complex. In this review we present and discuss… read more here.
Keywords: gut metabolome; host microbe; host; gut microbiota ... See more keywords
Introduction to host microbiome symbiosis in health and disease
Sign Up to like & getrecommendations! Published in 2020 at "Mucosal Immunology"
DOI: 10.1038/s41385-020-00365-4
Abstract: Humans share a core intestinal microbiome and yet human microbiome differs by genes, species, enterotypes (ecology), and gene count (microbial diversity). Achievement of microbiota metagenomic analysis has revealed that the microbiome gene count is a… read more here.
Keywords: symbiosis; introduction host; microbe symbiosis; host microbe ... See more keywords
A salivary metabolite signature that reflects gingival host-microbe interactions: instability predicts gingivitis susceptibility
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-59988-z
Abstract: Several proteins and peptides in saliva were shown to stimulate gingival wound repair, but the role of salivary metabolites in this process remains unexplored. In vitro gingival re-epithelialization kinetics were determined using unstimulated saliva samples… read more here.
Keywords: metabolite signature; microbe interactions; host microbe; signature ... See more keywords
Host-microbe interactions and the behavior of Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurogenetics"
DOI: 10.1080/01677063.2020.1802724
Abstract: Abstract Microbes are ubiquitous in the natural environment of Caenorhabditis elegans. Bacteria serve as a food source for C. elegans but may also cause infection in the nematode host. The sensory nervous system of C.… read more here.
Keywords: interactions behavior; microbe interactions; host microbe; caenorhabditis elegans ... See more keywords
Integrative multiomics analysis reveals host-microbe-metabolite interplays associated with the aging process in Singaporeans
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2070392
Abstract: ABSTRACT The age-associated alterations in microbiomes vary across populations due to the influence of genetics and lifestyles. To the best of our knowledge, the microbial changes associated with aging have not yet been investigated in… read more here.
Keywords: associated aging; host microbe; age; gut oral ... See more keywords
HMI-PRED 2.0: a biologist-oriented web application for prediction of host–microbe protein–protein interaction by interface mimicry
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac633
Abstract: Abstract Summary HMI-PRED 2.0 is a publicly available web service for the prediction of host–microbe protein–protein interaction by interface mimicry that is intended to be used without extensive computational experience. A microbial protein structure is… read more here.
Keywords: prediction host; host microbe; hmi pred; protein ... See more keywords