Dissecting cause and effect in host-microbiome interactions using the combined worm-bug model system
Sign Up to like & getrecommendations! Published in 2018 at "Biogerontology"
DOI: 10.1007/s10522-018-9752-x
Abstract: High-throughput molecular studies are greatly advancing our knowledge of the human microbiome and its specific role in governing health and disease states. A myriad of ongoing studies aim at identifying links between microbial community disequilibria… read more here.
Keywords: host microbiome; microbiome; effect host; model ... See more keywords
Impact of the Host Microbiome on Vaccine Responsiveness: Lessons Learned and Future Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00309
Abstract: Vaccination shows high variability in the elicited immune responses among individuals and populations for reasons still poorly understood. An increasing number of studies is supporting the evidence that gut microbiota, along with other interplaying variables,… read more here.
Keywords: microbiome vaccine; impact host; vaccine responsiveness; host microbiome ... See more keywords
Metabolic modeling reveals a multi-level deregulation of host-microbiome metabolic networks in IBD
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-025-60233-2
Abstract: Inflammatory bowel diseases (IBDs) are chronic disorders involving dysregulated immune responses. Despite the role of disrupted host-microbial interaction in the pathophysiology of IBD, the underlying metabolic principles are not fully understood. We densely profiled microbiome,… read more here.
Keywords: host microbiome; host; reveals multi; modeling reveals ... See more keywords
Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice
Sign Up to like & getrecommendations! Published in 2025 at "Nature Microbiology"
DOI: 10.1038/s41564-025-01959-z
Abstract: Aging is accompanied by considerable changes in the gut microbiome, yet the molecular mechanisms driving aging and the role of the microbiome remain unclear. Here we combined metagenomics, transcriptomics and metabolomics from aging mice with… read more here.
Keywords: host microbiome; host; metabolic modelling; mice metabolic ... See more keywords
Is Alzheimer’s disease a polymicrobial host microbiome dysbiosis?
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2020.1729741
Abstract: The question of whether Alzheimer’s disease (AD) is an infectious condition has been proposed previously but, received little support. This appears mainly due to an inability of being able to satis... read more here.
Keywords: host microbiome; alzheimer disease; disease polymicrobial; disease ... See more keywords
The Microbiome in Bronchial Biopsies from Smokers and Ex-Smokers with Stable COPD - A Metatranscriptomic Approach
Sign Up to like & getrecommendations! Published in 2022 at "COPD: Journal of Chronic Obstructive Pulmonary Disease"
DOI: 10.1080/15412555.2022.2033193
Abstract: Abstract Current knowledge about the respiratory microbiome is mainly based on 16S ribosomal RNA gene sequencing. Newer sequencing approaches, such as metatranscriptomics, offer the technical ability to measure the viable microbiome response to environmental conditions… read more here.
Keywords: host microbiome; smokers smokers; bronchial biopsies; stable copd ... See more keywords
GenBank as a source to monitor and analyze Host-Microbiome data
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac487
Abstract: MOTIVATION Microbiome datasets are often constrained by sequencing limitations. GenBank is the largest collection of publicly available DNA sequences, which is maintained by the National Center of Biotechnology Information (NCBI). The metadata of GenBank records… read more here.
Keywords: genbank; host microbiome; genbank source; microbiome data ... See more keywords
Principles and Terminology for Host–Microbiome–Drug Interactions
Sign Up to like & getrecommendations! Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad195
Abstract: Abstract Interactions between the microbiome and medical therapies are distinct and bidirectional. The existing term “pharmacomicrobiomics” describes the effects of the microbiome on drug distribution, metabolism, efficacy, and toxicity. We propose that the term “pharmacoecology”… read more here.
Keywords: microbiome drug; host microbiome; drug interactions; principles terminology ... See more keywords
Host-microbiome intestinal interactions during early life: considerations for atopy and asthma development.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000629
Abstract: PURPOSE OF REVIEW The body's largest microbial community, the gut microbiome, is in contact with mucosal surfaces populated with epithelial, immune, endocrine and nerve cells, all of which sense and respond to microbial signals. These… read more here.
Keywords: development; early life; host microbiome; atopy asthma ... See more keywords
Subgingival host-microbiome metatranscriptomic changes following scaling and root planning in Grade II/III Periodontitis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13737
Abstract: AIMS To assess the effects of scaling and root planning (SRP) on the dynamics of gene expression by the host and the microbiome in subgingival plaque samples. METHODS Fourteen periodontitis patients were closely monitored in… read more here.
Keywords: host microbiome; root planning; scaling root; periodontitis ... See more keywords
Genome evolution and host‐microbiome shifts correspond with intraspecific niche divergence within harmful algal bloom‐forming Microcystis aeruginosa
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Ecology"
DOI: 10.1111/mec.15198
Abstract: Intraspecific niche divergence is an important driver of species range, population abundance and impacts on ecosystem functions. Genetic changes are the primary focus when studying intraspecific divergence; however, the role of ecological interactions, particularly host‐microbiome… read more here.
Keywords: host microbiome; aeruginosa; divergence; intraspecific niche ... See more keywords