Standardization in host-microbiota interaction studies: challenges, gnotobiology as a tool, and perspective.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2018.07.007
Abstract: Considering the increasing list of diseases linked to the commensal microbiota, experimental studies of host-microbe interactions are of growing interest. Axenic and differently colonized animal models are inalienable tools to study these interactions. Factors, such… read more here.
Keywords: standardization; microbiota; standardization host; host microbiota ... See more keywords
Host-microbiota maladaptation in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2729-3
Abstract: Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is characterized by the accumulation of mutations and a dysregulated immune response. Up to 90% of disease risk is thought to be due… read more here.
Keywords: microbiota maladaptation; maladaptation colorectal; colorectal cancer; host microbiota ... See more keywords
Host and microbiota metabolic signals in aging and longevity
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemical Biology"
DOI: 10.1038/s41589-021-00837-z
Abstract: Aging is an inevitable biochemical process that adversely affects personal health and poses ever-increasing challenges to society. Recent research has revealed the crucial role of metabolism in regulating aging and longevity. During diverse metabolic processes,… read more here.
Keywords: longevity; host microbiota; metabolic signals; aging longevity ... See more keywords
Quorum sensing mediates gut bacterial communication and host-microbiota interaction.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2134981
Abstract: Gut bacteria employ quorum sensing (QS) to coordinate their activities and communicate with one another, this process relies on the production, detection, and response to autoinducers, which are extracellular signaling molecules. In addition to synchronizing… read more here.
Keywords: microbiota interaction; host microbiota; communication; quorum sensing ... See more keywords
The small intestine: dining table of host-microbiota meetings.
Sign Up to like & getrecommendations! Published in 2023 at "FEMS microbiology reviews"
DOI: 10.1093/femsre/fuad022
Abstract: Abstract Growing evidence suggests the importance of the small intestinal bacteria in the diet–host–microbiota dialogue in various facets of health and disease. Yet, this body site is still poorly explored and its ecology and mechanisms… read more here.
Keywords: small intestine; ecology; host microbiota; host ... See more keywords
Host‐microbiota interactions and adaptive immunity
Sign Up to like & getrecommendations! Published in 2017 at "Immunological Reviews"
DOI: 10.1111/imr.12575
Abstract: All mucosal surfaces are colonized with a vast number of microbes, which are essential for stimulating and regulating the immune system. While intrinsic and innate mechanisms exist to promote a strong barrier between the microbiota… read more here.
Keywords: interactions adaptive; microbiota interactions; host microbiota; host ... See more keywords
Th2 and metabolic responses to nematodes are independent of prolonged host microbiota abrogation
Sign Up to like & getrecommendations! Published in 2022 at "Parasite Immunology"
DOI: 10.1111/pim.12957
Abstract: Antibiotic treatment can lead to elimination of both pathogenic bacteria and beneficial commensals, as well as to altered host immune responses. Here, we investigated the influence of prolonged antibiotic treatment (Abx) on effector, memory and… read more here.
Keywords: abx; host microbiota; microbiota abrogation; infection ... See more keywords
Structural host-microbiota interaction networks
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005579
Abstract: Hundreds of different species colonize multicellular organisms making them “metaorganisms”. A growing body of data supports the role of microbiota in health and in disease. Grasping the principles of host-microbiota interactions (HMIs) at the molecular… read more here.
Keywords: host microbiota; microbiota interaction; host; structural host ... See more keywords
The Host Microbiota Contributes to Early Protection Against Lung Colonization by Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02656
Abstract: Tuberculosis (TB), caused by the airborne bacterial pathogen Mycobacterium tuberculosis, remains a major source of morbidity and mortality worldwide. So far, the study of host-pathogen interactions in TB has mostly focused on the physiology and… read more here.
Keywords: microbiota; host microbiota; colonization; tuberculosis ... See more keywords
Roles of Secretory Immunoglobulin A in Host-Microbiota Interactions in the Gut Ecosystem
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.880484
Abstract: In the gastrointestinal tract (GIT), the immune system interacts with a variety of microorganisms, including pathogens as well as beneficial symbionts that perform important physiological functions for the host and are crucial to sustain intestinal… read more here.
Keywords: secretory immunoglobulin; microbiota; gut microbiota; immunoglobulin host ... See more keywords
Editorial: Synthetic Live Biotherapeutic Products for Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.882743
Abstract: Host-microbiota interactions have increasingly been shown to play important roles in supporting host health (Brown et al., 2019; Janney et al., 2020). In human, the gut microbiota contributes to several metabolic and immune-mediated diseases, such… read more here.
Keywords: live biotherapeutic; microbiota interactions; microbiota; synthetic live ... See more keywords