Control of host mitochondria by bacterial pathogens.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in microbiology"
DOI: 10.1016/j.tim.2021.09.010
Abstract: Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support… read more here.
Keywords: control host; mitochondria bacterial; host mitochondria; microbiology ... See more keywords
A Toxoplasma Gondii Locus Required for the Direct Manipulation of Host Mitochondria Has Maintained Multiple Ancestral Functions
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Microbiology"
DOI: 10.2210/pdb6bxt/pdb
Abstract: The Toxoplasma gondii locus mitochondrial association factor 1 (MAF1) encodes multiple paralogs, some of which mediate host mitochondrial association (HMA). Previous work showed that HMA was a trait that arose in T. gondii through neofunctionalization… read more here.
Keywords: gondii locus; ancestral functions; host mitochondria; maf1 ... See more keywords
Targeting the Host Mitochondria as a Novel Human Cytomegalovirus Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15051083
Abstract: Human cytomegalovirus (HCMV) exploits host mitochondrial function to promote viral replication. HCMV gene products have been described to directly interact and alter functional or structural aspects of host mitochondria. Current antivirals against HCMV, such as… read more here.
Keywords: mitochondrial function; host mitochondrial; targeting host; human cytomegalovirus ... See more keywords