Multifunctional Bimetallic Nanoreactors for Integrative Host‐Pathogen Analysis Toward Bloodstream Infection Diagnosis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202417474
Abstract: Bloodstream infections (BSIs) annually claim millions of lives, contributing to one‐third of global mortality. Mortality rates predominantly depend on the duration between symptom onset and the administration of appropriate antibiotics. Clinical protocols for identifying pathogens… read more here.
Keywords: multifunctional bimetallic; host; bloodstream; pathogen ... See more keywords
The global network of domestic mammal hosts and zoonotic bacteria: implications for disease transmission and detection
Sign Up to like & getrecommendations! Published in 2025 at "Oikos"
DOI: 10.1002/oik.11077
Abstract: Zoonotic diseases, defined as those transmitted from animals to humans, represent over 75% of emerging infectious diseases and pose ongoing challenges to public health. Understanding the structure of host–pathogen interactions is critical for anticipating and… read more here.
Keywords: host; domestic mammal; network; host pathogen ... See more keywords
Integrated Host-Pathogen Metabolic Reconstructions.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7528-0_9
Abstract: The science and art of Genome scale metabolic network reconstructions have been explicitly documented in the literature for organisms across all the three kingdoms of life. Constraints-based models derived from such reconstructions have been used… read more here.
Keywords: pathogen; integrated host; biology; host ... See more keywords
Role of Mitochondria in Host-Pathogen Interaction.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8367-0_3
Abstract: The centrality of the mitochondrion in the evolution and control of the cellare now supported by many experimental studies. Not only with regard to the energy metabolism but also and especially with regard to the… read more here.
Keywords: role mitochondria; pathogen interaction; host; interaction ... See more keywords
In silico characterization, docking, and simulations to understand host–pathogen interactions in an effort to enhance crop production in date palms
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-021-04957-0
Abstract: Food safety remains a significant challenge despite the growth and development in agricultural research and the advent of modern biotechnological and agricultural tools. Though the agriculturist struggles to aid the growing population’s needs, many pathogen-based… read more here.
Keywords: pathogen; silico characterization; production; host ... See more keywords
The functional relevance of shrimp C-type lectins in host-pathogen interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103708
Abstract: C-type lectins (CTLs) are key recognition proteins in shrimp immunity. A few years ago we reviewed sequence information, ligand specificity, expression profiles and specific functions of the shrimp CTLs. Since then, multiple integrated studies that… read more here.
Keywords: functional relevance; host pathogen; type lectins; pathogen interactions ... See more keywords
Intrinsic disorder in proteins: Relevance to protein assemblies, drug design and host-pathogen interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2020.06.004
Abstract: Intrinsic disorder in proteins resulting in considerable variation in structure can lead to multiple functions including multi-specificity and diverse pathologies. Protein interfaces can involve disordered regions that assemble through a concerted-fold-and-bind mechanism. The binding involves… read more here.
Keywords: intrinsic disorder; disorder; drug design; host pathogen ... See more keywords
Molecular Evolution of Transition Metal Bioavailability at the Host-Pathogen Interface.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in microbiology"
DOI: 10.1016/j.tim.2020.08.001
Abstract: The molecular evolution of the adaptive response at the host-pathogen interface has been frequently referred to as an 'arms race' between the host and bacterial pathogens. The innate immune system employs multiple strategies to starve… read more here.
Keywords: evolution; molecular evolution; transition; metal ... See more keywords
Pharmacological Targeting of the Host-Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2017.02.003
Abstract: The rise of multidrug-resistant pathogens and the dearth of new antibiotic development place an existential strain on successful infectious disease therapy. Breakthrough strategies that go beyond classical antibiotic mechanisms are needed to combat this looming… read more here.
Keywords: pathogen; pathogen interaction; host; pharmacological targeting ... See more keywords
Host-Pathogen Interaction Activated Biosynthesis of Natural Products.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.5c00776
Abstract: The way immune cells attack pathogenic microorganisms might trigger pathogens to produce compounds that promote their survival. Based on this idea, we constructed a coculture system of pathogenic fungi and immune cells and isolated fumigatinolactone… read more here.
Keywords: immune cells; natural products; pathogen; host pathogen ... See more keywords
Stronger together
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Microbiology"
DOI: 10.1038/nrmicro.2017.95
Abstract: Susceptibility to infectious diseases and disease severity may be affected by interactions between the genomes of the host and pathogen. Although the effect of variations in gene sequence on disease has been studied for several… read more here.
Keywords: analysis; stronger together; genome; host pathogen ... See more keywords