Host and viral non‐coding RNAs in dengue pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2360
Abstract: Dengue virus (DENV) is a mosquito‐borne flavivirus that causes frequent outbreaks in tropical countries. Due to the four different serotypes and ever‐mutating RNA genome, it is challenging to develop efficient therapeutics. Early diagnosis is crucial… read more here.
Keywords: coding rnas; host viral; host; viral non ... See more keywords
Within-Host Viral Dynamics in a Multi-compartmental Environment
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-019-00658-1
Abstract: The discrepancy in the turnover of cells and virus in different organs or viral reservoirs necessitates the investigation of multiple compartments within a host. Establishing a multi-compartmental structure that describes the complexity of various organs,… read more here.
Keywords: host viral; viral dynamics; multi compartmental; within host ... See more keywords
The dual role of phytochemicals on SARS-CoV-2 inhibition by targeting host and viral proteins
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Traditional and Complementary Medicine"
DOI: 10.1016/j.jtcme.2021.09.001
Abstract: Background The severe acute respiratory syndrome-2019 has affected more than 190 million people around the world and caused severe crises throughout the globe. Due to rapid mutation in the viral genome, it became important to… read more here.
Keywords: role phytochemicals; phytochemicals sars; host viral; dual role ... See more keywords
A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins.
Sign Up to like & getrecommendations! Published in 2021 at "Structure"
DOI: 10.1016/j.str.2021.01.010
Abstract: The extraterminal (ET) domain of BRD3 is conserved among BET proteins (BRD2, BRD3, BRD4), interacting with multiple host and viral protein-protein networks. Solution NMR structures of complexes formed between the BRD3 ET domain and either… read more here.
Keywords: host viral; brd3; binding motif; common binding ... See more keywords
Host and viral traits predict zoonotic spillover from mammals
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature22975
Abstract: The majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, HIV, Ebola and SARS). Understanding patterns of viral diversity in wildlife and determinants of… read more here.
Keywords: viral traits; host viral; predict zoonotic; zoonotic viruses ... See more keywords
Rescuing low frequency variants within intra-host viral populations directly from Oxford Nanopore sequencing data
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28852-1
Abstract: Infectious disease monitoring on Oxford Nanopore Technologies (ONT) platforms offers rapid turnaround times and low cost. Tracking low frequency intra-host variants provides important insights with respect to elucidating within-host viral population dynamics and transmission. However,… read more here.
Keywords: oxford nanopore; host viral; intra host; frequency ... See more keywords
Interaction of the Host and Viral Genome and Their Influence on HIV Disease
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00720
Abstract: The course of Human Immunodeficiency Virus type 1 (HIV) infection is a dynamic interplay in which both host and viral genetic variation, among other factors, influence disease susceptibility and rate of progression. HIV set-point viral… read more here.
Keywords: host viral; hiv; infection; disease ... See more keywords
Risk Factors of Severe COVID-19: A Review of Host, Viral and Environmental Factors
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15010175
Abstract: The clinical course and outcome of COVID-19 are highly variable, ranging from asymptomatic infections to severe disease and death. Understanding the risk factors of severe COVID-19 is relevant both in the clinical setting and at… read more here.
Keywords: severe covid; viral environmental; host viral; risk factors ... See more keywords