Host – virus – drug interactions as determinants of COVID-19’s phenotypes: A data-driven hypothesis
Sign Up to like & getrecommendations! Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.110275
Abstract: There is a growing body of evidence on the significance of interactions between comorbidities, their treatments and COVID-19 clinical phenotypes. The hypothesis explored herein is that pharmaceutical compounds currently in use are affecting COVID-19 susceptibility… read more here.
Keywords: interactions determinants; drug interactions; host virus; virus drug ... See more keywords
Targeting host-virus interactions: in silico analysis of the binding of human milk oligosaccharides to viral proteins involved in respiratory infections
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-54624-6
Abstract: Respiratory viral infections, a major public health concern, necessitate continuous development of novel antiviral strategies, particularly in the face of emerging and re-emerging pathogens. In this study, we explored the potential of human milk oligosaccharides… read more here.
Keywords: viral proteins; host; silico analysis; human milk ... See more keywords
Data Proliferation, Reconciliation, and Synthesis in Viral Ecology
Sign Up to like & getrecommendations! Published in 2021 at "BioScience"
DOI: 10.1093/biosci/biab080
Abstract: The fields of viral ecology and evolution are rapidly expanding, motivated in part by concerns around emerging zoonoses. One consequence is the proliferation of host–virus association data, which underpin viral macroecology and zoonotic risk prediction… read more here.
Keywords: host virus; data proliferation; ecology; viral ecology ... See more keywords
Zinc finger proteins in the host-virus interplay: multifaceted functions based on their nucleic acid-binding property.
Sign Up to like & getrecommendations! Published in 2021 at "FEMS microbiology reviews"
DOI: 10.1093/femsre/fuaa059
Abstract: Zinc finger proteins (ZFPs) are a huge family comprised of massive, structurally diverse proteins characterized by zinc ion coordinating. They engage in the host-virus interplay in-depth and occupy a significant portion of the host antiviral… read more here.
Keywords: host virus; zinc finger; virus interplay; finger proteins ... See more keywords
The Multifaceted Roles of Galectins in Host-Virus Interactions: A Comprehensive Overview.
Sign Up to like & getrecommendations! Published in 2025 at "Glycobiology"
DOI: 10.1093/glycob/cwaf026
Abstract: Galectins are a family of β-galactosides-binding protein, crucial regulators of host-virus interactions. They achieve this by recognizing specific glycan patterns on viral surfaces or mediating interactions with intracellular viral or host proteins, subsequently influencing the… read more here.
Keywords: multifaceted roles; viral infections; virus interactions; roles galectins ... See more keywords
Evolutionary Landscapes of Host-Virus Arms Races.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of immunology"
DOI: 10.1146/annurev-immunol-072621-084422
Abstract: Vertebrate immune systems suppress viral infection using both innate restriction factors and adaptive immunity. Viruses mutate to escape these defenses, driving hosts to counterevolve to regain fitness. This cycle recurs repeatedly, resulting in an evolutionary… read more here.
Keywords: arms races; virus arms; landscapes host; host virus ... See more keywords
Transcriptomic analyses of host-virus interactions during in vitro infection with wild-type and glycoprotein g-deficient (ΔgG) strains of ILTV in primary and continuous cell cultures
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0311874
Abstract: Infectious laryngotracheitis (ILT) remains a significant concern for the poultry industry worldwide due to its impact on animal welfare and its substantial economic consequences. The disease is caused by the alphaherpesvirus, infectious laryngotracheitis virus (ILTV).… read more here.
Keywords: type; cell; infection; virus interactions ... See more keywords
Editorial: The application of OMICS technologies to interrogate host-virus interactions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1050012
Abstract: COPYRIGHT © 2022 Gomes, Alfson and Junqueira. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: technologies interrogate; omics technologies; application omics; interrogate host ... See more keywords
Three-dimensional and single-cell sequencing of liver cancer reveals comprehensive host-virus interactions in HBV infection
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1161522
Abstract: Backgrounds Hepatitis B virus (HBV) infection is a major risk factor for chronic liver diseases and liver cancer (mainly hepatocellular carcinoma, HCC), while the underlying mechanisms and host-virus interactions are still largely elusive. Methods We… read more here.
Keywords: cell; hbv infection; infection; host virus ... See more keywords
Editorial: Host-virus interaction at the omics and ecology levels
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1209532
Abstract: COPYRIGHT © 2023 de Medeiros, Valverde-Villegas and Ellwanger. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted,… read more here.
Keywords: ecology; editorial host; interaction omics; omics ecology ... See more keywords
Type I interferon signaling in SARS-CoV-2 associated neurocognitive disorder (SAND): Mapping host-virus interactions to an etiopathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.1063298
Abstract: Epidemiological, clinical, and radiological studies have provided insights into the phenomenology and biological basis of cognitive impairment in COVID-19 survivors. Furthermore, its association with biomarkers associated with neuroinflammation and neurodegeneration supports the notion that it… read more here.
Keywords: cov associated; interferon; sand; host virus ... See more keywords