When Cold Is Hot: Immune Checkpoint Inhibition Therapy for Rhabdoid Tumors.
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DOI: 10.1016/j.ccell.2019.11.006
Abstract: Carcinogen-induced cancers typically have high mutation burdens and an inflamed microenvironment and thus are poised to respond to immune checkpoint inhibitors (ICIs). However, cancers with loss-of-function mutations in the SWI/SNF complex have few additional mutations… read more here.
Keywords: immune checkpoint; cold hot; checkpoint inhibition; checkpoint ... See more keywords