Articles with "hotairm1" as a keyword



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Investigating function of long noncoding RNA of HOTAIRM1 in progression of SKOV3 ovarian cancer cells.

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Published in 2021 at "Drug development research"

DOI: 10.1002/ddr.21821

Abstract: Ovarian cancer is one of the most heterogeneous malignancies in the field of gynecologic oncology. Deregulation of long noncoding RNAs (lncRNAs) is implicated in carcinogenesis. Therefore, the present study was conducted to investigate the possible… read more here.

Keywords: hotairm1; ovarian cancer; skov3; hotairm1 progression ... See more keywords
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Long non-coding RNA HOTAIRM1 promotes proliferation and inhibits apoptosis of glioma cells by regulating the miR-873-5p/ZEB2 axis

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Published in 2020 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000000615

Abstract: Abstract Background Glioblastoma is one of the most common malignant brain tumors. Conventional clinical treatment of glioblastoma is not sufficient, and the molecular mechanism underlying the initiation and development of this disease remains unclear. Our… read more here.

Keywords: expression; mir 873; glioblastoma; zeb2 ... See more keywords
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N6‐methyladenosine‐modified HOTAIRM1 promotes vasculogenic mimicry formation in glioma

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Published in 2022 at "Cancer Science"

DOI: 10.1111/cas.15578

Abstract: Vasculogenic mimicry (VM) has been reported to accelerate angiogenesis in malignant tumors, yet the mechanism underlying VM has not been fully elucidated. N6‐methyladenosine (m6A) mainly modulates mRNA fate and affects multiple tumorigenesis. Here, we aimed… read more here.

Keywords: formation glioma; modified hotairm1; formation; hotairm1 ... See more keywords

HOTAIRM1 Maintained the Malignant Phenotype of tMSCs Transformed by GSCs via E2F7 by Binding to FUS

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Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/7734413

Abstract: Objective Mesenchymal stromal/stem cells (MSCs) are an important part of the glioma microenvironment and are involved in the malignant progression of glioma. In our previous study, we showed that MSCs can be induced to a… read more here.

Keywords: phenotype tmscs; tmscs; e2f7; malignant phenotype ... See more keywords
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LncRNA HOTAIRM1 inhibits the progression of hepatocellular carcinoma by inhibiting the Wnt signaling pathway.

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Published in 2018 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_201808_15622

Abstract: OBJECTIVE To explore the possible role of long non-coding RNA (lncRNA) HOTAIRM1 in the pathogenesis of hepatocellular carcinoma (HCC) and its underlying mechanism. PATIENTS AND METHODS LncRNA HOTAIRM1 expressions in 30 pairs of hepatocellular carcinoma… read more here.

Keywords: hotairm1; hepatocellular carcinoma; hcc; apoptosis ... See more keywords
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Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma

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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2021.798584

Abstract: ORAL squamous cell carcinoma (OSCC) is a malignant tumor with the highest incidence among tumors involving the oral cavity maxillofacial region, and is notorious for its high recurrence and metastasis potential. Long non-coding RNAs (lncRNAs),… read more here.

Keywords: cell; oscc; squamous cell; oral squamous ... See more keywords

Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.00473

Abstract: HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA that has been shown to be a key regulator of myeloid cell development by targeting HOXA1. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous… read more here.

Keywords: hotairm1; rna; lung cancer; myeloid ... See more keywords