Articles with "hotspot exonuclease" as a keyword



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Characterization of hotspot exonuclease domain mutations in the DNA polymerase ϵ gene in endometrial cancer

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1018034

Abstract: Objective This study was aimed to profile hotspot exonuclease domain mutations (EDMs) of the DNA polymerase ϵ gene (POLE) in endometrial cancer (EC) and to investigate the effects of EDMs on tumor cell behavior and… read more here.

Keywords: endometrial cancer; hotspot; hotspot exonuclease; exonuclease domain ... See more keywords