Articles with "hotspots cho" as a keyword



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A compendium of stable hotspots in the CHO genome.

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Published in 2023 at "Biotechnology and bioengineering"

DOI: 10.1002/bit.28390

Abstract: The use of targeted integration for industrial CHO cell line development currently requires significant upfront effort to identify genomic loci capable of supporting multigram per liter therapeutic protein production from a limited number of transgene… read more here.

Keywords: compendium stable; cell; hotspot; stable hotspots ... See more keywords