USP25 inhibits DNA damage by stabilizing BARD1 protein in a house dust mite‐induced asthmatic model in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11775
Abstract: House dust mites (HDM) can cause DNA double‐strand breaks in the lungs of asthmatic patients. However, the molecular mechanisms driving DNA damage and repair in HDM‐induced asthma are yet to be elucidated. Thus, in this… read more here.
Keywords: vivo; hdm; damage; dna damage ... See more keywords
MIF is essential to the establishment of house dust mite-induced airway inflammation and tissue remodeling in mice.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250016
Abstract: Macrophage migration inhibitory factor (MIF) is present in high amounts in the bronchoalveolar lavage fluid (BALF) and serum of asthmatic patients contributing to the pathogenesis of experimental asthma induced by ovalbumin (OVA) in mice. Whether… read more here.
Keywords: hdm challenged; house dust; mif; mice ... See more keywords
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Immunology"
DOI: 10.1002/eji.202451205
Abstract: Enhancing mesenchymal stromal cell (MSC) therapeutic efficacy through licensing with proinflammatory cytokines is now well established. We have previously shown that macrophage migration inhibitory factor (MIF)‐licensed MSCs exerted significantly enhanced therapeutic efficacy in reducing inflammation… read more here.
Keywords: house dust; mif; mesenchymal stromal; dust mite ... See more keywords
High prevalence of house dust mite sensitization in children with severe asthma living at high altitude in a tropical country
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24079
Abstract: Some studies, mainly in Europe, have shown a low level of sensitization to house dust mite (HDM) allergens at high altitude (HA). Differently, some others in tropical countries have shown a higher level. The aim… read more here.
Keywords: dust mite; house dust; severe asthma; children severe ... See more keywords
Novel Method for the Purification of House Dust Mite Allergen Der p 1 and Its Use in Structure-Based Chemical Design of Novel Inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9591-2_14
Abstract: House dust mites are globally significant triggers of allergic disease. Notable among their extensive repertoire of allergens are the Group 1 cysteine peptidase allergens which function as digestive enzymes in house dust mites. Compelling evidence… read more here.
Keywords: house dust; method purification; novel inhibitors; der use ... See more keywords
Storage mite concentrations are underestimated compared to house dust mite concentrations
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and Applied Acarology"
DOI: 10.1007/s10493-019-00376-2
Abstract: Dwellings are increasingly well insulated to save energy and this leads to higher humidity and temperature, which improves conditions for mites. Dermatophagoides antigens are the main allergens involved and tested in atopic asthma. We developed… read more here.
Keywords: dust mite; storage mite; mite concentrations; house dust ... See more keywords
Update on House Dust Mite Allergen Avoidance Measures for Asthma
Sign Up to like & getrecommendations! Published in 2020 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-020-00948-y
Abstract: Purpose of Review To critically review the evidence in favor or against the use of house dust mite (HDM) allergen avoidance measures in patients with asthma. Recent Findings Systematic reviews and meta-analyses suggested no positive… read more here.
Keywords: allergen; allergen avoidance; mite allergen; house dust ... See more keywords
Allergic Rhinitis and House Dust Mite Sensitization Determine Persistence of Asthma in Children
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Pediatrics"
DOI: 10.1007/s12098-021-04052-5
Abstract: To specify clinical and immunological parameters of the mechanisms, which may lead to development of persistent asthma, or regression of the disease symptoms. Eighty children with childhood asthma, diagnosed in the past by using the… read more here.
Keywords: house dust; dust mite; allergic rhinitis; persistence ... See more keywords
Socio-environmental profile of child and adolescents sensitized by house dust mite in northeast of Brazil.
Sign Up to like & getrecommendations! Published in 2019 at "Allergologia et immunopathologia"
DOI: 10.1016/j.aller.2019.02.001
Abstract: INTRODUCTION The association regarding the atopic sensitization to mite aeroallergens and the socio-environmental features is still inconsistent. OBJECTIVES We analyzed the role played by socioeconomic and environmental factors in the prevalence of sensitization to house… read more here.
Keywords: socio environmental; ci95; house dust; dust mite ... See more keywords
Concentrations and loadings of organophosphate and replacement brominated flame retardants in house dust from the home study during the PBDE phase-out.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.124701
Abstract: Polybrominated diphenyl ethers, a class of flame retardants and endocrine disruptors, have been substituted in new products by organophosphate (OPFR) and replacement brominated flame retardants (RBFR). OPFRs and RBFRs readily migrate from consumer products into… read more here.
Keywords: concentrations loadings; house dust; range; replacement brominated ... See more keywords
Plastic additives and personal care products in south China house dust and exposure in child-mother pairs.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.116347
Abstract: Indoor environment constitutes an important source of industrial additive chemicals to human exposure. We hypothesized that the influence of residential environment on human exposure varies among different types of additive chemicals and differs between children… read more here.
Keywords: south china; house dust; child mother; mother pairs ... See more keywords