Dynamics of HOX gene expression and regulation in adipocyte development.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.145308
Abstract: HOX proteins are homeodomain-containing transcription factors that play a central role in development. We have applied genome-wide approaches to develop time-dependent profile of differentially expressed genes in early and mature adipocytes. The list of differentially… read more here.
Keywords: gene expression; expression; gene; hox gene ... See more keywords
Selective interactions between diverse STEs organize the ANT-C Hox cluster
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33588-4
Abstract: The three-dimensional organization of the eukaryotic genome is important for its structure and function. Recent studies indicate that hierarchies of chromatin loops underlie important aspects of both genomic organization and gene regulation. Looping between insulator… read more here.
Keywords: chromatin; hox; insulator; gene ... See more keywords
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny.
Sign Up to like & getrecommendations! Published in 2022 at "Essays in biochemistry"
DOI: 10.1042/ebc20220050
Abstract: The importance of Hox genes for the development and evolution of the vertebrate axial skeleton and paired appendages has been recognized for already several decades. The steady growth of genomic sequence data from an increasing… read more here.
Keywords: shaping hox; vertebrate; gene activity; activity ... See more keywords
The Insulator Protein CTCF Is Required for Correct Hox Gene Expression, but Not for Embryonic Development in Drosophila
Sign Up to like & getrecommendations! Published in 2018 at "Genetics"
DOI: 10.1534/genetics.118.301350
Abstract: Insulator binding proteins (IBPs) play an important role in regulating gene expression by binding to specific DNA sites to facilitate appropriate gene regulation. There are several IBPs in Drosophila, each defined by their ability to… read more here.
Keywords: drosophila; gene expression; ctcf; gene ... See more keywords
Changes in Hox Gene Chromatin Organization during Odontogenic Lineage Specification
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14010198
Abstract: Craniofacial tissues comprise highly evolved organs characterized by a relative lack of expression in the HOX family transcription factors. In the present study, we sought to define the epigenetic events that limit HOX gene expression… read more here.
Keywords: alveolar bone; neural crest; gene expression; hox gene ... See more keywords
HOX-Gene Cluster Organization and Genome Duplications in Fishes and Mammals: Transcript Variant Distribution along the Anterior–Posterior Axis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179990
Abstract: Hox genes play a crucial role in morphogenesis, especially in anterior–posterior body axis patterning. The organization of Hox clusters in vertebrates is a result of several genome duplications: two rounds of duplication in the ancestors… read more here.
Keywords: anterior posterior; fishes mammals; distribution along; hox gene ... See more keywords