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   Articles with "hoxa10" as a keyword



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Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas.

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recommendations! Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109873

Abstract: Long non-coding RNAs (lncRNAs) are increasingly recognized as functional units in cancer and powerful biomarkers; however, most remain uncharacterized. Here, we analyze 5,592 prognostic lncRNAs in 9,446 cancers of 30 types using machine learning. We… read more here.

Keywords: pan cancer; gliomas; hoxa10; non coding ... See more keywords
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MicroRNA-582-3p regulates osteoporosis through regulating homeobox A10 and osteoblast differentiation

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recommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"

DOI: 10.1080/08923973.2022.2052895

Abstract: Abstract Objective Recent studies have demonstrated that micro RNAs (miRNAs) are involved in bone formation and bone cell differentiation, but the role of miR-582-3p in osteoporosis is unclear. We want to study the mechanism of… read more here.

Keywords: mir 582; hoxa10; expression; osteoporosis regulating ... See more keywords
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LncRNA HOXA10-AS promotes the progression of esophageal carcinoma by regulating the expression of HOXA10

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recommendations! Published in 2023 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2108633

Abstract: ABSTRACT Esophageal cancer (EC) remains a primary cause of cancer-associated fatality worldwide and is characterized by poor prognosis. HOXA10-AS is reported to be relevant with the development of different human cancers. However, its role and… read more here.

Keywords: progression esophageal; hoxa10; lncrna hoxa10; hoxa10 promotes ... See more keywords
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LncRNA HOXA10-AS functions as an oncogene by binding miR-6509-5p to upregulate Y-box binding protein 1 in gastric cancer

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2059615

Abstract: ABSTRACT Gastric cancer (GC) is one of the serious malignant diseases, accounting for several cases globally. The prevention, discovery and cure of GC depend on its molecular mechanism. In recent decades, it has been increasingly… read more here.

Keywords: hoxa10; lncrna hoxa10; box binding; gastric cancer ... See more keywords
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Abstract 4646: Loss of nuclear HoxA10 is associated with proliferation of testicular germ cell tumors

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recommendations! Published in 2019 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs18-4646

Abstract: Background: HOXA10 is a key transcriptional factor that regulates testis development as reported from previous transgenic mouse models and human inherited diseases. However, whether it also plays important roles in promoting the development of testicular… read more here.

Keywords: cancer; proliferation; cell; hoxa10 ... See more keywords
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miR-135a inhibits the proliferation of HBV-infected hepatocellular carcinoma cells by targeting HOXA10

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recommendations! Published in 2023 at "Translational Cancer Research"

DOI: 10.21037/tcr-22-2789

Abstract: Background The incidence of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV) is extremely high. MicroRNAs (miRNAs) are a type of endogenous non-coding small RNA with novel molecular therapeutic mechanisms that plays an… read more here.

Keywords: mir 135a; hoxa10; proliferation; hbv ... See more keywords
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LINC00461 facilitates head and neck squamous cell carcinoma development and reduces chemosensitivity by impairing miR-195-mediated inhibition of HOXA10

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recommendations! Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.01442

Abstract: Homeobox A10 (HOXA10) is an oncogene in head and neck squamous cell carcinoma (HNSCC). This study was designed to explore the interaction among long intergenic noncoding RNA 00461 (LINC00461), microRNA (miR)-195, and HOXA10, as well… read more here.

Keywords: mir 195; chemoresistance hnscc; hoxa10; head neck ... See more keywords
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Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.750208

Abstract: Background: Endometriosis affects endometrial receptivity, a key factor for successful embryo implantation. Metformin treatment is associated with alleviating the symptoms of endometriosis; however the mechanism of metformin action is unclear. Neoangiogenesis plays an important role… read more here.

Keywords: hoxa10; endometriosis; factor; endometrial receptivity ... See more keywords
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Homeobox A10 promotes the proliferation and invasion of bladder cancer cells via regulation of matrix metalloproteinase-3

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recommendations! Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2019.10312

Abstract: Homeobox A10 (HOXA10) belongs to the family of HOX genes, which are closely connected with embryonic development and serve important roles in various tumors. However, the role of HOXA10 in bladder cancer (BC) remains unclear.… read more here.

Keywords: bladder cancer; hoxa10; homeobox a10; matrix metalloproteinase ... See more keywords