miR-10b suppresses cell invasion and metastasis through targeting HOXA3 regulated by FAK/YAP signaling pathway in clear-cell renal cell carcinoma
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DOI: 10.1186/s12882-019-1322-1
Abstract: BackgroundMicroRNAs have been related to tumor progression in diverse human cancers including clear-cell renal cell carcinoma (ccRCC). Previous study has suggested the important regulation function of miR-10b in ccRCC. However, the direct target of miR-10b… read more here.
Keywords: invasion; mir 10b; hoxa3; yap ... See more keywords
Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation
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DOI: 10.1371/journal.pone.0186818
Abstract: Hemogenic endothelium (HE) undergoes endothelial-to-hematopoietic transition (EHT) to generate blood, a process that requires progressive down-regulation of endothelial genes and induction of hematopoietic ones. Previously, we have shown that the transcription factor HoxA3 prevents blood… read more here.
Keywords: notch activation; blood; hoxa3; blood formation ... See more keywords