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   Articles with "hoxb5" as a keyword



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Transcriptional activation of EGFR by HOXB5 and its role in breast cancer cell invasion.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.08.071

Abstract: HOX genes are transcription factors that play important roles in body patterning and many cellular processes during embryonic, fetal, and adult development. Given their important function in normal tissues, it is reasonable to assume that… read more here.

Keywords: hoxb5; invasion; breast cancer; expression ... See more keywords
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Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes

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recommendations! Published in 2018 at "Nature Immunology"

DOI: 10.1038/s41590-018-0046-x

Abstract: Deletion of master regulators of the B cell lineage reprograms B cells into T cells. Here we found that the transcription factor Hoxb5, which is expressed in uncommitted hematopoietic progenitor cells but is not present… read more here.

Keywords: hoxb5; factor hoxb5; transcription factor; cell ... See more keywords
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Circ_0020123 enhances the cisplatin resistance in non-small cell lung cancer cells partly by sponging miR-140-3p to regulate homeobox B5 (HOXB5)

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2036910

Abstract: ABSTRACT Cisplatin (DDP) therapy is widely used for the treatment of non-small cell lung cancer (NSCLC), but the curative effect is limited by chemoresistance. This study was designed to explore circ_0020123 function in DDP resistance… read more here.

Keywords: resistance; hoxb5; cell; ddp ... See more keywords
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Hoxb5 reprogrammes murine multipotent blood progenitors into haematopoietic stem cell‐like cells

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recommendations! Published in 2022 at "Cell Proliferation"

DOI: 10.1111/cpr.13235

Abstract: The expression of transcription factor Hoxb5 specifically marks the functional haematopoietic stem cells (HSC) in mice. However, our recent work demonstrated that ectopic expression of Hoxb5 exerted little effect on HSC but could convert B‐cell… read more here.

Keywords: cell; haematopoietic stem; multipotent blood; hoxb5 ... See more keywords
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miR-200a-3p- and miR-181-5p-Mediated HOXB5 Upregulation Promotes HCC Progression by Transcriptional Activation of EGFR

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.822760

Abstract: Background Hepatocellular carcinoma (HCC) remains a worldwide burden. However, the mechanisms behind the malignant biological behavior of HCC remain unclear. The homeobox (HOX) family could act as either promoters or suppressors in different kinds of… read more here.

Keywords: hcc progression; mir 181; 200a mir; mir ... See more keywords