Knockdown of HOXB8 inhibits tumor growth and metastasis by the inactivation of Wnt/β-catenin signaling pathway in osteosarcoma.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.04.004
Abstract: Homeobox B8 (HOXB8) is a member of HOX family and was reported to be dysregulated in human cancers. However, its expression pattern and function in human osteosarcoma (OS) remain unknown. The aim of the current… read more here.
Keywords: catenin signaling; hoxb8; signaling pathway; knockdown hoxb8 ... See more keywords
Corticostriatal circuit defects in Hoxb8 mutant mice
Sign Up to like & getrecommendations! Published in 2018 at "Molecular psychiatry"
DOI: 10.1038/mp.2017.180
Abstract: Hoxb8 mutant mice exhibit compulsive grooming and hair removal dysfunction similar to humans with the obsessive-compulsive disorder (OCD)-spectrum disorder, trichotillomania. As, in the mouse brain, the only detectable cells that label with Hoxb8 cell lineage… read more here.
Keywords: corticostriatal circuit; mutant mice; hoxb8; circuit ... See more keywords
SNHG3/miR-2682-5p/HOXB8 promotes cell proliferation and migration in oral squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Oral diseases"
DOI: 10.1111/odi.13656
Abstract: OBJECTIVE The potential molecular mechanism underlying the disease progression of oral squamous cell carcinoma (OSCC) remains largely elusive. The purpose of the study is to figure out the role and molecular mechanism of homeobox B8… read more here.
Keywords: mir 2682; proliferation migration; hoxb8;