HOXC10 indicates poor survival outcome in gastric cancer and promotes G1/S cell cycle transition through transcriptional repression of p21.
Sign Up to like & getrecommendations! Published in 2022 at "Neoplasma"
DOI: 10.4149/neo_2022_220609n615
Abstract: Homeobox (HOX) genes encode proteins that function as transcription factors during embryogenesis and tumorigenesis. We have previously reported upregulation of HOXC10 in gastric cancer (GC) tissues using cDNA microarray analysis. Though the functional role of… read more here.
Keywords: hoxc10; cycle transition; cell cycle;
HOXC10 Promotes Metastasis in Colorectal Cancer by Recruiting Myeloid-derived Suppressor Cells
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DOI: 10.7150/jca.76945
Abstract: Background: Since metastasis is the primary cause of death in human colorectal cancer (CRC) patients, the exact mechanism underlying CRC metastasis remains unclear. Here, we provide evidence for a unique function of HomeoboxC10 (HOXC10) in… read more here.
Keywords: metastasis; crc metastasis; colorectal cancer; hoxc10 ... See more keywords