Articles with "hoxc8 promoter" as a keyword



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ASH2L-Promoted HOXC8 Gene Expression Plays a Role in Mixed Lineage Leukemia-Rearranged Acute Leukemia

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Published in 2020 at "OncoTargets and therapy"

DOI: 10.2147/ott.s221643

Abstract: Background Mixed lineage leukemia (MLL) fusion protein alone exhibits poor histone lysine methyltransferase (HKMT) activity in catalyzing histone H3 Lys4 trimethylation (H3K4me3) in MLL-rearranged acute leukemia. Methods To explore the HKMT effect of another regulatory… read more here.

Keywords: leukemia; rearranged acute; expression; acute leukemia ... See more keywords