A heterozygous duplication variant of the HOXD13 gene caused synpolydactyly type 1 with variable expressivity in a Chinese family
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medical Genetics"
DOI: 10.1186/s12881-019-0908-6
Abstract: BackgroundSynpolydactyly type 1 (SPD1), also known as syndactyly type II, is an autosomal dominant limb deformity generally results in webbing of 3rd and 4th fingers, duplication of 4th or 5th toes. It is most commonly… read more here.
Keywords: hoxd13 gene; hoxd13; variant; family ... See more keywords
Variants Identified in the HOXC13 and HOXD13 Genes Suggest Association with Cervical Cancer in a Cohort of Mexican Women
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14020358
Abstract: HOX genes have been associated with carcinogenesis. However, the molecular mechanism by which tumors are generated remains unclear. The HOXC13 and HOXD13 genes are of interest for their involvement in the development of genitourinary structures.… read more here.
Keywords: cervical cancer; mexican women; hoxc13 hoxd13; hoxd13 genes ... See more keywords