Prophylactic administration of HPA-1a-specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice.
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DOI: 10.1182/blood.2022015666
Abstract: Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a life-threatening bleeding disorder caused by maternal alloantibodies directed against paternally inherited human platelet alloantigens (HPAs) present on the surface of fetal and neonatal platelets. There are currently no approved… read more here.
Keywords: hpa specific; specific antibodies; alloimmune thrombocytopenia; hpa ... See more keywords