Asiaticoside induces osteogenic differentiation of human periodontal ligament cells through the Wnt pathway
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DOI: 10.1002/jper.17-0471
Abstract: BACKGROUND Asiaticoside is a compound isolated from Herb Centella asiatica, which has been shown to promote osteogenic differentiation of human periodontal ligament (hPDL) cells. This study investigated the molecular mechanism underlying the asiaticoside-induced osteogenic differentiation… read more here.
Keywords: periodontal ligament; hpdl cells; differentiation human; osteogenic differentiation ... See more keywords
Vibration enhances PGE2, IL‐6, and IL‐8 expression in compressed hPDL cells via cyclooxygenase pathway
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DOI: 10.1002/jper.17-0653
Abstract: BACKGROUND Although vibration combined with orthodontic force may accelerate orthodontic tooth movement, little is known about the mechanisms that regulate the associated cellular responses. The goal of this study was to investigate whether mechanical vibration… read more here.
Keywords: hpdl cells; mechanical vibration; vibration; pge2 ... See more keywords
Lipase-a single-nucleotide polymorphism rs143793106 is associated with increased risk of aggressive periodontitis by negative influence on the cytodifferentiation of human periodontal ligament cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.13079
Abstract: BACKGROUND AND OBJECTIVE Aggressive periodontitis (AgP) is characterized by general health and rapid destruction of periodontal tissue. The familial aggregation of this disease highlights the involvement of genetic factors in its pathogeny. We conducted a… read more here.
Keywords: cytodifferentiation; transfected hpdl; rs143793106; lipa snp ... See more keywords
Sphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells
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DOI: 10.1177/0022034516677938
Abstract: Sphingomyelin phosphodiesterase 3 (Smpd3), which encodes neutral sphingomyelinase 2 (nSMase2), is a key molecule for skeletal development as well as for the cytodifferentiation of odontoblasts and alveolar bone. However, the effects of nSMase2 on the… read more here.
Keywords: periodontal ligament; hpdl cells; cytodifferentiation periodontal; cytodifferentiation ... See more keywords
Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials
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DOI: 10.1186/s12967-018-1551-2
Abstract: BackgroundHuman periodontal ligament stem cells (hPDLSCs) have been shown to be a reliable source of mesenchymal stem cells (MSCs). On the other hand, rabbits have been commonly used in preclinical trials for musculoskeletal research. However,… read more here.
Keywords: hpdl cells; periodontal ligament; rpdl cells; ligament stem ... See more keywords