Periodontal ligament cells derived small extracellular vesicles are involved in orthodontic tooth movement.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of orthodontics"
DOI: 10.1093/ejo/cjac041
Abstract: OBJECTIVES Small extracellular vesicles (EVs) from human periodontal ligament cells (hPDLCs) are closely associated with periodontal homeostasis. Far less is known about EVs association with orthodontic tooth movement (OTM). This study aimed to explore the… read more here.
Keywords: hpdlcs; otm; small evs; tooth movement ... See more keywords
The effect of liraglutide on the proliferation, migration, and osteogenic differentiation of human periodontal ligament cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Periodontal Research"
DOI: 10.1111/jre.12607
Abstract: OBJECTIVE Liraglutide (LIRA) is a novel antidiabetic therapy that may have anti-inflammatory and bone protective effects. Thus, we studied the potential therapeutic effect of LIRA on periodontitis by assessing the effects of LIRA on the… read more here.
Keywords: proliferation; effect; migration; expression ... See more keywords
Effects of DDR1 on migration and adhesion of periodontal ligament cells and the underlying mechanism.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.12986
Abstract: BACKGROUND AND OBJECTIVE As one of the widely expressed cell surface receptors binding to collagen, the most abundant component of the extracellular matrix (ECM), knowledge of the expression, functions, and mechanisms underlying the role of… read more here.
Keywords: ddr1; hpdlcs; migration adhesion; mek ... See more keywords
Oxidative stress state inhibits exosome secretion of hPDLCs through a specific mechanism mediated by PRMT1.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.13040
Abstract: BACKGROUND AND OBJECTIVES Periodontitis, the most common chronic inflammation characterized by persistent alveolar bone resorption in the periodontitis, affects almost half of the adult population worldwide. Oxidative stress is one of the pathophysiological mechanisms underlying… read more here.
Keywords: hpdlcs; exosome secretion; oxidative stress; prmt1 ... See more keywords
METTL3 promotes the osteogenic differentiation of human periodontal ligament cells by increasing YAP activity via IGF2BP1 and YTHDF1-mediated m6A modification.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of periodontal research"
DOI: 10.1111/jre.13297
Abstract: AIMS N6-Methyladenosine (m6A) has been confirmed to play a dynamic role in osteoporosis and bone metabolism. However, whether m6A is involved in the osteogenic differentiation of human periodontal ligament cells (hPDLCs) remains unclear. The present… read more here.
Keywords: differentiation; mettl3; m6a modification; yap ... See more keywords
Nicotine regulates autophagy of human periodontal ligament cells through α7 nAchR that promotes secretion of inflammatory factors IL-1β and IL-8
Sign Up to like & getrecommendations! Published in 2021 at "BMC Oral Health"
DOI: 10.1186/s12903-021-01894-5
Abstract: Background Nicotine is an important risk factor and the main toxic component associated with periodontitis. However, the mechanism of nicotine induced periodontitis is not clear. To investigated the mechanism through which nicotine regulates autophagy of… read more here.
Keywords: regulates autophagy; nicotine; nicotine regulates; inflammatory factors ... See more keywords
MiR-143-3p Inhibits Osteogenic Differentiation of Human Periodontal Ligament Cells by Targeting KLF5 and Inactivating the Wnt/β-Catenin Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.606967
Abstract: Human periodontal ligament cells (hPDLCs) play a vital role in cell regeneration and tissue repair with multi-directional differentiation potential. microRNAs (miRs) are implicated in the osteogenesis of hPDLCs. This study explored the mechanism of miR-143-3p… read more here.
Keywords: mir 143; osteogenic differentiation; klf5; hpdlcs ... See more keywords