Chemical Modulation of the Human Oligopeptide Transporter 1, hPepT1.
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DOI: 10.1021/acs.molpharmaceut.7b00775
Abstract: In humans, peptides derived from dietary proteins and peptide-like drugs are transported via the proton-dependent oligopeptide transporter hPepT1 (SLC15A1). hPepT1 is located across the apical membranes of the small intestine and kidney, where it serves… read more here.
Keywords: oligopeptide transporter; hpept1; transporter hpept1; modulation human ... See more keywords
Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides
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DOI: 10.3390/pharmaceutics14081610
Abstract: The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs. Moreover, it might be addressed in… read more here.
Keywords: cyclic peptides; slc15a1; substrate characteristics; substrate ... See more keywords