Clinical variability and molecular characterization of Hbs/Gγ (Aγδβ)0-thal and Hbs/HPFH in Indian sickle cell disease patients: AIIMS experience
Sign Up to like & getrecommendations! Published in 2019 at "Hematology"
DOI: 10.1080/16078454.2019.1579985
Abstract: ABSTRACT Introduction: In sickle cell disease (SCD) patients, among the predictors of survival, HbF levels play a significant role in lowering the morbidity and mortality. Coinheritance of δβ thalassemia and hereditary persistence of fetal hemoglobin… read more here.
Keywords: hbs; thal; hbs hpfh; disease ... See more keywords
A Single -195 C < G HBG1 Promoter Mediated By CRISPR/Cas9 Genome Editing Induces Fetal Hemoglobin Synthesis in Hudep-2
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-118534
Abstract: Sickle cell disease (SCD) is a serious condition, chronic and undoubtedly represents a public health problem worldwide. SCD is caused by a point mutation in codon 6 of the β globin gene resulting in the… read more here.
Keywords: crispr cas9; hbg1; hudep; hpfh ... See more keywords