Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers.
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DOI: 10.1016/j.stemcr.2022.01.012
Abstract: In vitro expansion of human primordial germ cell-like cells (hPGCLCs), a pluripotent stem cell-derived PGC model, has proved challenging due to rapid loss of primordial germ cell (PGC)-like identity and limited cell survival/proliferation. Here, we describe… read more here.
Keywords: germ cell; hpgclcs; like cells; primordial germ ... See more keywords