Occurrence and molecular characterization of human pegivirus‐1 (HPgV‐1) viremia in healthy volunteer blood donors from Northern Portugal
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27687
Abstract: Human pegivirus‐1 (HPgV‐1) is a member of the Flaviviridae family and the Pegivirus genus. Despite having been discovered 25 years ago, there is still much to know regarding HPgV‐1 clinical impact, as this virus is… read more here.
Keywords: blood donors; hpgv; pegivirus; molecular characterization ... See more keywords
Development of a high-throughput multiplexed real time RT-PCR assay for detection of human pegivirus 1 and 2.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2016.12.013
Abstract: Human Pegivirus 2 (HPgV-2) was recently identified in the bloodstream of HCV-infected and multiply transfused individuals. Initial reports show HPgV-2 circulates at a low prevalence in HCV co-infected individuals, necessitating testing of large cohorts of… read more here.
Keywords: detection; hpgv; development high; human pegivirus ... See more keywords
RNA-Dependent RNA Polymerase of the Second Human Pegivirus Exhibits a High-Fidelity Feature
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02729-22
Abstract: RNA viruses represent the most important pathogens for humans and animals and exhibit rapid evolution and high adaptive capacity, which is due to the high mutation rates for using the error-prone RNA-dependent RNA polymerase (RdRp)… read more here.
Keywords: hpgv; fidelity; rna polymerase; rdrp ... See more keywords
Human pegivirus (HPgV, GBV-C) RNA in volunteer blood donors from a public hemotherapy service in Northern Brazil
Sign Up to like & getrecommendations! Published in 2020 at "Virology Journal"
DOI: 10.1186/s12985-020-01427-6
Abstract: Background Human pegivirus (HPgV)—formerly known as GBV-C—is a member of the Flaviviridae family and belongs to the species Pegivirus C. It is a non-pathogenic virus and is transmitted among humans mainly through the exposure to… read more here.
Keywords: blood donors; hpgv; pegivirus hpgv; blood ... See more keywords
Difference of Intrahost Dynamics of the Second Human Pegivirus and Hepatitis C Virus in HPgV-2/HCV-Coinfected Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.728415
Abstract: Background The second human pegivirus (HPgV-2) and hepatitis C virus (HCV) belong to the Flaviviridae family and share some common genome features. However, the two viruses exhibit significantly different genetic diversity. The comparison of intrahost… read more here.
Keywords: second human; hpgv hcv; hpgv; intrahost ... See more keywords
Human pegivirus-1 replication influences NK cell reconstitution after allogeneic haematopoietic stem cell transplantation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1060886
Abstract: Introduction Human pegivirus-1 (HPgV-1) is a so-called commensal virus for which no known associated organ disease has been found to date. Yet, it affects immune-reconstitution as previously studied in the HIV population, in whom active… read more here.
Keywords: cell; reconstitution; hpgv; allo hsct ... See more keywords
Human Pegivirus Type 1: A Common Human Virus That Is Beneficial in Immune-Mediated Disease?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.887760
Abstract: Two groups identified a novel human flavivirus in the mid-1990s. One group named the virus hepatitis G virus (HGV) and the other named it GB Virus type C (GBV-C). Sequence analyses found these two isolates… read more here.
Keywords: hpgv; infection; virus; type ... See more keywords
The Second Human Pegivirus, a Non-Pathogenic RNA Virus with Low Prevalence and Minimal Genetic Diversity
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14091844
Abstract: The second human pegivirus (HPgV-2) is a virus discovered in the plasma of a hepatitis C virus (HCV)-infected patient in 2015 belonging to the pegiviruses of the family Flaviviridae. HPgV-2 has been proved to be… read more here.
Keywords: hpgv; rna; virus; rna virus ... See more keywords