Design, synthesis, and biological evaluation of Helicobacter pylori inosine 5′‐monophosphate dehydrogenase (HpIMPDH) inhibitors
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DOI: 10.1002/ddr.21467
Abstract: Inosine 5′‐monophosphate dehydrogenase (IMPDH) catalyzes a crucial step in the biosynthesis of guanine nucleotides. Being a validated target for immunosuppressive, antiviral, and anticancer drug development, lately it has been exploited as a promising target for… read more here.
Keywords: hpimpdh inhibitors; monophosphate dehydrogenase; hpimpdh; inosine monophosphate ... See more keywords