Novel RP‐HPLC method for estimation of a newly developed combination of tizanidine and etoricoxib in rat plasma: Eight criteria for greens evaluation
Sign Up to like & getrecommendations! Published in 2024 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202400025
Abstract: A novel environmentally friendly reversed‐phase high‐performance liquid chromatography (RP‐HPLC) method has been effectively validated for simultaneously measuring a prospective conjunction of tizanidine (TIZ) and etoricoxib (ETC), the combined medicine, in rat plasma. The technique employs… read more here.
Keywords: tiz etc; hplc; method; hplc method ... See more keywords
Preparative separation of four isomers of synthetic anisodamine by HPLC and diastereomer crystallization.
Sign Up to like & getrecommendations! Published in 2019 at "Chirality"
DOI: 10.1002/chir.23026
Abstract: Anisodamine (654-1), a well-known cholinergic antagonist, is marketed as synthetic anisodamine (mixture of four isomers, 654-2) in China. To preparative resolution and comparison of the bioactivities of the four isomers of synthetic anisodamine, current work… read more here.
Keywords: isomers synthetic; hplc; anisodamine; separation ... See more keywords
Determination of panthenol enantiomers in cosmetic preparations using an achiral-chiral-coupled column HPLC system.
Sign Up to like & getrecommendations! Published in 2019 at "Chirality"
DOI: 10.1002/chir.23152
Abstract: A new high-performance liquid chromatography (HPLC) method for separation and determination of panthenol enantiomers in hair care products was developed. Two types of detectors, low-wavelength ultraviolet (UV) and polarimetric, were used. Optimized conditions consisted of… read more here.
Keywords: hplc; panthenol enantiomers; achiral chiral; determination panthenol ... See more keywords
Efficient preparation of stereopure amphiphilic 1,2-amino alcohols by using preparative enantioselective HPLC.
Sign Up to like & getrecommendations! Published in 2021 at "Chirality"
DOI: 10.1002/chir.23395
Abstract: Chiral amphiphiles are useful for controlling the structures and properties of supramolecular assemblies, but their stereocontrolled synthesis is generally difficult, because their long alkyl chains tend to bring unfavorable effects on the solubility, reactivity, and… read more here.
Keywords: amphiphilic amino; amino alcohols; overall yield; hplc ... See more keywords
Design, Synthesis, and Applications of Bis-Amido HPLC Pirkle-Type Chiral Stationary Phases.
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DOI: 10.1002/chir.23715
Abstract: Two different types of chiral stationary phases, based on Pirkle's design, were created by attaching chiral selectors to 3-mercapto silica gel. To prepare the enantiomeric selectors, 3,5-dinitrobenzoyl and naphthyl groups were sequentially added to a… read more here.
Keywords: hplc; chiral stationary; stationary phases; chiral selectors ... See more keywords
Enantiomeric quality control of R‐Tofisopam by HPLC using polysaccharide‐type chiral stationary phases in polar organic mode
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800220
Abstract: A novel, fast and economic chiral HPLC method was developed and validated for the resolution of the four isomers of tofisopam. The separation capacity of eleven different chiral columns: six polysaccharide‐type including three amylose‐based (Chiralpak… read more here.
Keywords: hplc; mode; polar organic; polysaccharide type ... See more keywords
Reversed-Phase HPLC: A fast and efficient analytical method to quantify docetaxel-loaded pegylated liposomes in release study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100382
Abstract: Docetaxel is an anticancer that belongs to the family of taxanes and acts in the inhibition of cell proliferation through the polymerization of microtubules. The aim of this study was the development and validation a… read more here.
Keywords: hplc; analytical method; reversed phase; pegylated liposomes ... See more keywords
A sensitive and selective HPLC-MS3 method for therapeutic drug monitoring of meropenem and its validation by comparison with HPLC-MS2 methods.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200064
Abstract: Meropenem, a representative β-lactam antibiotic, is widely used to treat complicated and serious infections. Therefore, it is a great significance to monitor the plasma drug concentration for individualized antimicrobial therapy. This study first describes the… read more here.
Keywords: monitoring meropenem; validation; hplc; method ... See more keywords
Simultaneous Determination of Hormones in Botanical Dietary Supplements With Supramolecular Solvent-Based Extraction by HPLC-MS/MS.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of separation science"
DOI: 10.1002/jssc.70110
Abstract: Dietary supplements typically contain either natural products or synthetic chemicals. While botanical dietary supplements are often thought to be more natural and safer, they could still contain potentially harmful ingredients. Despite the detection of sex… read more here.
Keywords: hormones botanical; hplc; dietary supplements; botanical dietary ... See more keywords
Measurement of Superoxide Production and NADPH Oxidase Activity by HPLC Analysis of Dihydroethidium Oxidation.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6625-7_19
Abstract: The fluorogenic probe dihydroethidium (DHE) is widely used for detecting intracellular superoxide. DHE oxidation by superoxide generates specifically the compound 2-hydroxyethidium (2-E+OH), so that 2-E+OH detection confers specificity to superoxide assessment among many other reactive… read more here.
Keywords: hplc; oxidation; dihydroethidium; superoxide ... See more keywords
Stavros Kromidas (Ed.): The HPLC expert: possibilities and limitations of modern high performance liquid chromatography
Sign Up to like & getrecommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0397-4
Abstract: Book’s topic High-performance liquid chromatography (HPLC) has been widely practiced for more than 50 years, and is now one of the most widespread analytical techniques. The practice of HPLC is no longer limited to chromatographers… read more here.
Keywords: chromatography; hplc; high performance; liquid chromatography ... See more keywords