A novel thiolysis-HPLC method for the determination of proanthocyanidins in grape seeds.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200003
Abstract: A novel thiolysis-HPLC method for quantitative determination of total proanthocyanidins and mean degree of polymerization in grape seeds has been developed. Following thiolysis with formic acid and benzyl mercaptan, reaction products were separated and purified.… read more here.
Keywords: hplc method; thiolysis hplc; thiolysis; novel thiolysis ... See more keywords
An HPLC method for simultaneous quantification of metformin and ferulic acid in solid dosage forms.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200373
Abstract: Metformin is one of the most commonly used drugs in the world for the treatment of type 2 diabetes, while ferulic acid is a molecule that stands out for its antioxidant potential. Recent studies demonstrate… read more here.
Keywords: method simultaneous; simultaneous quantification; acid; hplc method ... See more keywords
Development and Validation of an HPLC Method for Simultaneous Determination of Ibuprofen and 17 Related Compounds
Sign Up to like & getrecommendations! Published in 2017 at "Chromatographia"
DOI: 10.1007/s10337-017-3358-3
Abstract: A reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for determination of ibuprofen and 17 related compounds (chemical process impurities and degradation products) simultaneously. This method may be used for quality control of… read more here.
Keywords: hplc method; ibuprofen related; method; related compounds ... See more keywords
Rapid HPLC Method for Simultaneous Quantification of trans-Resveratrol and Quercetin in the Skin of Red Grapes
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DOI: 10.1007/s12161-017-1022-z
Abstract: The vine produces de novo compounds with small molecules, called phytoalexins, as defense response to oxidative stress, microbial infections, and UV irradiation. Such bioactive substances are trans-resveratrol and quercetin. In this study, a rapid HPLC… read more here.
Keywords: grape; resveratrol quercetin; rapid hplc; hplc method ... See more keywords
Development and Optimization of a Reversed-Phase HPLC Method to Separate Pulse Proteins
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DOI: 10.1007/s12161-020-01771-x
Abstract: Due to the demand for new sources of non-GMO and allergen-free plant proteins in food formulations that have not previously existed, there is a growing need for analytical methods to characterize these proteins. A reversed-phase… read more here.
Keywords: phase; reversed phase; method; optimization ... See more keywords
Forced degradation study with a developed and validated RP-HPLC method for determination of cefpodoxime proxetil in the bulk and finished pharmaceutical products
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-019-01630-5
Abstract: The present study aimed to develop an HPLC method of Cfp analysis which enjoyed highly linearity, repeatability, robustness, ruggedness, selectivity, rapidly, and economic to use. The chromatographic method uses a column Inertsil ODS-3 (250 mm × 4.6 mm × 5 µm). The… read more here.
Keywords: forced degradation; bulk; method; degradation study ... See more keywords
Development of a HPLC-MS/MS method for assessment of thiol redox status in human tear fluids.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2021.114295
Abstract: Oxidative stress is reported to be part of the pathology of many ocular diseases. For the diagnosis of ocular diseases, tear fluid has unique advantages. Although numerous analytical methods exist for the measurement of different… read more here.
Keywords: tear fluids; thiol redox; hplc method;
HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2021.114338
Abstract: The Ras superfamily of small G proteins play central roles in diverse signaling pathways. Superfamily members act as molecular on-off switches defined by their occupancy with GTP or GDP, respectively. In vitro functional studies require… read more here.
Keywords: resolve identify; nucleotides bound; hplc method; identify quantify ... See more keywords
A simple RP-HPLC method for related substances of zoledronic acid in pharmaceutical products
Sign Up to like & getrecommendations! Published in 2017 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2012.07.022
Abstract: Abstract A novel, selective and sensitive reverse phase-high performance liquid chromatography (RP-HPLC) method has been developed for the validated estimation of imidazol-1-yl-acetic acid in zoledronic acid formulations. The separation was achieved on a 5 μ C18… read more here.
Keywords: zoledronic acid; method related; simple hplc; hplc method ... See more keywords
Stability indicating RP-HPLC method for simultaneous determination of guaifenesin and pseudoephedrine hydrochloride in the presence of syrup excepients
Sign Up to like & getrecommendations! Published in 2017 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2013.11.019
Abstract: Abstract The present work concerns with the development of stability indicating the RP-HPLC method for simultaneous determination of guaifenesin (GUF) and pseudoephedrine hydrochloride (PSH) in the presence of guaifenesin related substance (Guaiacol). GUC, and in… read more here.
Keywords: determination; syrup excepients; syrup; method ... See more keywords
Applying green analytical chemistry (GAC) for development of stability indicating HPLC method for determining clonazepam and its related substances in pharmaceutical formulations and calculating uncertainty
Sign Up to like & getrecommendations! Published in 2019 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2014.10.051
Abstract: Abstract Clonazepam contains one benzodiazepine ring in its chemical structure which makes it vulnerable to degradation. In this study, green analytical chemistry approach was applied in attempts for the development of validated stability indicating RP-HPLC… read more here.
Keywords: green analytical; related substances; method; clonazepam ... See more keywords