Influence of solvent mixtures on HPMCAS-celecoxib microparticles prepared by electrospraying
Sign Up to like & getrecommendations! Published in 2018 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2018.01.007
Abstract: Hypromellose acetate succinate (HPMCAS) microparticles containing the poorly-water soluble drug celecoxib (CEL) were prepared by electrospraying intended for oral drug delivery. Various solvent mixtures with different solubility for CEL and HPMCAS were used to induce… read more here.
Keywords: drug; solvent mixtures; hpmcas; prepared electrospraying ... See more keywords
Development of modified release 3D printed tablets (printlets) with pharmaceutical excipients using additive manufacturing.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.05.021
Abstract: The aim of this study was to manufacture 3D printed tablets (printlets) from enteric polymers by single filament fused deposition modeling (FDM) 3D printing (3DP). Hot melt extrusion was used to generate paracetamol-loaded filaments from… read more here.
Keywords: tablets printlets; drug; additive manufacturing; hpmcas ... See more keywords
Impact of HPMCAS on the Dissolution Performance of Polyvinyl Alcohol Celecoxib Amorphous Solid Dispersions
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DOI: 10.3390/pharmaceutics12060541
Abstract: Amorphous solid dispersions (ASDs) have been proven to increase the bioavailability of poorly soluble drugs. It is desirable that the ASD provide a rapid dissolution rate and a sufficient stabilization of the generated supersaturation. In… read more here.
Keywords: solid dispersions; amorphous solid; asds; polyvinyl alcohol ... See more keywords