Ramelteon protects against human pulmonary microvascular endothelial cell injury induced by lipopolysaccharide (LPS) via activating nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway
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DOI: 10.1080/21655979.2021.2021065
Abstract: ABSTRACT Acute lung injury (ALI) is classified as a moderate or mild acute respiratory distress syndrome and is a prominent cause of morbidity and mortality among the critically ill population. Ramelteon is a melatonin receptor… read more here.
Keywords: hpmecs; cell; ramelteon; factor ... See more keywords
PECAM EMPs regulate apoptosis in pulmonary microvascular endothelial cells in COPD by activating the Akt signaling pathway
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DOI: 10.18332/tid/146959
Abstract: INTRODUCTION Endothelial microparticles (EMPs) are partly associated with the progress of chronic obstructive pulmonary disease (COPD). We sought to measure the levels of EMPs in COPD patients and in human pulmonary microvascular endothelial cells (HPMECs)… read more here.
Keywords: hpmecs; apoptosis; expression; pecam emps ... See more keywords
Inhibition of S100A12 Attenuates LPS-Induced Endothelial Barrier Dysfunction in HPMECs through the JAK2/STAT3 Signaling Pathway.
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DOI: 10.2174/0115665240338945250317082242
Abstract: BACKGROUND The calcium-binding protein S100A12 plays a pivotal role in the progression of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). However, the underlying mechanisms are yet to be fully elucidated. OBJECTIVE This… read more here.
Keywords: hpmecs; s100a12; endothelial barrier; jak2 stat3 ... See more keywords